• Daminozide (CAS 1596-84-5) - TCI D4015 - AMI Scientific
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CAS 1596-84-5

Daminozide TCI D4015

Daminozide TCI D4015
Rp 2.038.050,00
Rp 2.038.050,00
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Daminozide is a hydrazide derivative of succinic acid that has long been recognized as a plant growth regulator, and which over the past several decades has attracted considerable attention in molecular biology as an inhibitor of histone demethylase enzymes. In plant research, the compound is used to study the control of stem elongation and vegetative growth through its influence on gibberellin biosynthesis. In epigenetics research, daminozide serves as a small molecule that inhibits a subgroup of JmjC domain-containing demethylase enzymes, allowing investigators to trace the role of histone modifications in the regulation of gene expression within cells.

The properties that make daminozide a frequently chosen reagent are its small molecular size, its good solubility in aqueous media, and its selectivity toward particular demethylase subfamilies compared with broad-spectrum inhibitor compounds. This selectivity matters because it allows researchers to attribute observed changes to a more specific enzyme target rather than to a wholesale disruption of the entire epigenetic pathway. As a solid material, daminozide is also relatively straightforward to weigh out and prepare into stock solutions, which supports consistent handling across repeated experiments and simplifies the preparation of working dilutions at the bench.

In Indonesian laboratories, this product from TCI is typically used in university research groups, molecular biology and epigenetics laboratories, and plant science facilities that investigate growth regulation. It is generally purchased as a research-grade reagent for chromatin and gene expression studies, for comparative screening of demethylase inhibitors, and for plant physiology work examining vegetative growth. The solid form suits laboratories that prepare their own stock solutions and store aliquots for use across successive experimental runs.

  • Epigenetics research on histone demethylation — daminozide inhibits a subgroup of JmjC domain-containing demethylase enzymes, letting researchers examine how histone modifications regulate gene expression in cells.
  • Selective inhibitor studies — its selectivity toward particular demethylase subfamilies allows observed cellular changes to be linked to a more specific enzyme target rather than to broad pathway disruption.
  • Plant growth regulation studies — as a long-established plant growth regulator, the compound supports investigation of stem elongation control and vegetative growth in experimental plant systems.
  • Gibberellin biosynthesis research — daminozide exerts its plant growth effects through influence on gibberellin biosynthesis, making it useful for studies dissecting this hormonal pathway.
  • Aqueous stock solution preparation for cell-based assays — its good solubility in aqueous media and solid physical form make it convenient to weigh accurately and dissolve for treatment work.

Brand TCI
CAS number 1596-84-5
Molecular formula —
Purity —
Category Life Science > Molecular Biology > Epigenetics
Pack sizes Available in standard TCI research pack sizes; please confirm the currently offered packaging when ordering
Physical form Solid
Storage Store as directed on the manufacturer's product label and accompanying documentation
  • Product Code: D4015

Store daminozide in its original tightly closed container, kept in a cool, dry, and well-ventilated place away from direct sunlight, moisture, and incompatible materials, following the storage conditions stated on the manufacturer's label and safety data sheet. Because the material is supplied as a solid, use a clean dry spatula and weighing vessel to avoid contaminating the bulk container, and reseal it promptly after each use. Prepared aqueous stock solutions should be transferred to suitable labelled containers, clearly marked with contents and preparation date, and stored according to the requirements of the intended experiment. Handle the compound in a well-ventilated area or fume hood, wearing a laboratory coat, safety glasses, and appropriate gloves, and avoid generating dust or breathing any airborne particles. Wash hands thoroughly after handling, keep the material away from food and drink, and dispose of residues and contaminated consumables in accordance with applicable institutional and local chemical waste regulations. Always review the full safety data sheet before first use.

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