TCI
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Description
TCI D4061 Diacerein is an anthraquinone-derived compound classified as a pharmaceutical research reagent for experimental use. Structurally, the molecule is the acetylated form of rhein, and in biological systems it is known to undergo deacetylation into its active metabolite. In the laboratory, this compound is used as a reference material and as a test compound in pharmacological research, particularly in studies concerned with inflammatory processes and the metabolism of joint tissue. Supplied as an analytical-grade reagent, it allows researchers to design experiments that are reproducible and comparable between laboratories.
The characteristics that make this compound a preferred choice are the clarity of its chemical identity and the properties conferred by its anthraquinone framework. The conjugated ring system produces absorption in the ultraviolet and visible regions, so the compound is relatively easy to detect and quantify using high-performance liquid chromatography with an absorbance detector. The two acetyl groups on the molecule act as important sites of chemical change, because their hydrolysis yields a derivative compound with different solubility and activity. This property is precisely what makes diacerein an interesting subject for study, since a single starting material can be followed through a defined chemical transformation within an experimental system.
In Indonesian laboratories, this reagent is typically used in academic and institutional research settings where pharmacological and biochemical studies are carried out. It serves researchers preparing analytical methods, running comparative assays, and building experimental designs that require a well-characterized reference compound. Because the identity of the material is clearly defined, it supports work that must be documented, repeated, and cross-checked against results generated in other laboratories, both within Indonesia and internationally.
Laboratory Applications
- Pharmacological research on inflammatory processes, where a clearly identified anthraquinone derivative is required as a defined test compound in experimental study designs.
- Studies of joint tissue metabolism, in which diacerein serves as the experimental substance of interest for laboratory investigations conducted under controlled conditions.
- HPLC method development and validation, since the conjugated anthraquinone ring system absorbs in the ultraviolet and visible regions and is readily detected by absorbance detectors.
- Reference material for analytical identification and comparison, providing a chemically well-defined standard that supports reproducible results across different laboratories and instruments.
- Deacetylation and hydrolysis studies, because the two acetyl groups on the molecule are defined sites of chemical change yielding a derivative of different solubility and activity.
Specifications
- Brand: TCI
- CAS number: 13739-02-1
- Product code: D4061
- Category: Life Science > Biochemicals and Reagents > Pharmaceutical Research Reagents (for Experimental Use)
- Pack sizes: available in the standard research pack sizes offered by the manufacturer for this catalogue item
- Storage: store according to the conditions stated on the manufacturer's label and safety data sheet
Handling and Storage
Store the reagent in its original tightly closed container, kept in a cool, dry, and well-ventilated place away from direct sunlight, moisture, and incompatible materials. Amber glass or the manufacturer's supplied packaging is suitable for protecting the compound from light, which is advisable for an anthraquinone derivative. Handle the material only in a laboratory setting by trained personnel, using appropriate personal protective equipment such as gloves, safety glasses, and a laboratory coat, and weigh or transfer powders in a fume hood or suitable enclosure. Avoid generating dust, keep containers closed when not in use, and always consult the manufacturer's safety data sheet before handling or disposal. This product is intended for experimental research use only.
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