TCI D4081, CAS 551-92-8, is 1,2-Dimethyl-5-nitroimidazole supplied with the designation [for Biochemical Research]. This compound belongs to the nitroimidazole class, a group of molecules widely recognised in antimicrobial and antiprotozoal investigation. Within the product catalogue it is listed under Life Science, in the biochemicals and antibiotic reagents group, and it is intended specifically for research purposes and laboratory testing. In practical laboratory work it serves as a test compound in mechanistic studies, as a comparison material in residue analysis, and as a starting material for the synthesis of other nitroimidazole derivatives.
The characteristics that determine its selection are the imidazole ring structure carrying a nitro group at position 5 and two methyl groups at positions 1 and 2. This aromatic nitro group is the focus of scientific attention because it can undergo enzymatic reduction under anaerobic conditions, a pathway that forms the basis of many studies into the mode of action of the nitroimidazole class. From a practical laboratory standpoint, the solid form allows the material to be weighed accurately for the preparation of stock solutions, and the chromophore group present in the molecule provides absorbance that supports spectroscopic observation.
In Indonesian laboratories, material of this type is generally used in university research groups, analytical service laboratories, and institutional research units working on antimicrobial and antiprotozoal topics. It is typically handled as part of method development work, as a comparison material for residue analysis of nitroimidazole compounds, and as a starting point for synthetic work on related derivatives. Because it is designated for biochemical research, its use is confined to research and laboratory testing rather than any therapeutic or production application.
- Mechanistic antimicrobial studies: the aromatic nitro group can undergo enzymatic reduction under anaerobic conditions, making this compound a suitable test substance for investigating how nitroimidazoles exert their effect.
- Residue analysis reference material: as a defined nitroimidazole compound in solid form, it serves as a comparison material when analytical methods for nitroimidazole residues are developed and evaluated in the laboratory.
- Synthetic starting material: the substituted imidazole ring with methyl groups at positions 1 and 2 provides a defined framework from which other nitroimidazole derivatives can be prepared by laboratory synthesis.
- Antiprotozoal research: because the nitroimidazole class is widely recognised in antiprotozoal investigation, this member of the class is appropriate as a study compound in research programmes addressing that subject area.
- Spectroscopic method work: the chromophore group in the molecule gives absorbance that supports spectroscopic observation, which makes the compound useful when detection and measurement procedures are being established.
| Brand | TCI |
|---|---|
| CAS number | 551-92-8 |
| Molecular formula | — |
| Purity | — |
| Category | Life Science > Biochemicals and Reagents > Antibiotics |
| Pack sizes | available in the catalogue pack sizes offered for this product code; please confirm the required quantity when ordering |
| Physical form | solid, allowing accurate weighing for the preparation of stock solutions |
| Storage | — |
- Chemical name: 1,2-Dimethyl-5-nitroimidazole, designated [for Biochemical Research]
Store the material in its original tightly closed container, kept in a cool, dry and well-ventilated area away from direct sunlight, moisture and sources of heat or ignition. Chemically resistant containers with secure closures are appropriate, and the container should be reclosed immediately after each weighing so that the solid does not take up atmospheric moisture. Weighing and solution preparation should be carried out in a fume hood by trained personnel wearing a laboratory coat, safety glasses and suitable chemical-resistant gloves. Avoid inhalation of dust and contact with skin and eyes, keep the compound separate from incompatible materials, and dispose of residues and contaminated items according to applicable laboratory waste procedures. As the product is designated for biochemical research, it must be used only for research and laboratory testing.
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