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Description
TCI D4823 is PSI-6206, a pyrimidine nucleoside analog widely referenced in antiviral research literature, particularly in studies of inhibitors that block viral replication through a chain-termination mechanism. As a biochemical reagent, this material is used in laboratories as a reference compound, an analytical standard, and a starting material for the stepwise preparation of derivatives. Within the biochemicals and reagents category, compounds of this type serve an important role as research tools that allow investigators to examine how nucleoside analogs interact with viral polymerase enzymes and to trace the metabolic pathways such compounds follow inside cellular systems.
The characteristic that makes this compound a frequent choice is its nucleoside structure, which is modified at the sugar portion and therefore produces enzymatic recognition behavior that differs from that of naturally occurring nucleosides. This modification gives the material a distinctive value in structure–activity relationship studies, because researchers can directly compare its behavior with that of unmodified bases and sugars. Supplied as a solid, the compound can be weighed accurately at the milligram scale and dissolved conveniently for the preparation of stock solutions, which supports reproducible dosing across repeated experimental series.
In Indonesian laboratories, a reagent of this kind is typically handled within university research groups, government research institutes, and private analytical facilities that carry out biochemical and antiviral investigations. Its availability in a solid, accurately weighable form makes it practical for settings where small quantities are consumed across many experiments over an extended period. Researchers commonly integrate it into method development work, comparative assays, and synthetic routes leading to related derivative compounds.
Laboratory Applications
Antiviral research reference compound — the material serves as a well-characterized nucleoside analog against which investigators benchmark the behavior of newly prepared or less familiar candidate compounds.
Viral polymerase interaction studies — its sugar-modified nucleoside structure allows researchers to examine how enzymes recognize, accept, or reject analogs relative to natural nucleoside substrates.
Structure–activity relationship investigations — comparing this modified analog with unmodified bases and sugars lets research teams map which structural features drive the observed biochemical behavior.
Synthetic starting material for derivatives — the compound provides a defined solid platform from which laboratories build derivative structures through stepwise chemical preparation and subsequent purification.
Analytical standard preparation — accurate milligram-scale weighing and straightforward dissolution make the solid suitable for preparing stock solutions used in calibration and comparative analysis.
Specifications
Brand: TCI
CAS number: 863329-66-2
Category: Life Science > Biochemicals and Reagents > Antibiotics
Product code: D4823
Physical form: solid, suitable for accurate milligram-scale weighing
Pack sizes: available in standard research quantities; please confirm the specific pack size when ordering
Storage: store according to the manufacturer's stated conditions on the product label
Handling and Storage
Store the container in a cool, dry, and well-ventilated area, kept tightly closed and protected from moisture and direct light, following the storage conditions stated by the manufacturer on the product label. Use clean, chemically compatible containers such as amber glass vials for prepared stock solutions, and label them clearly with contents and preparation date. Handle the solid in a fume hood or a properly ventilated workspace while wearing gloves, safety glasses, and a laboratory coat. Avoid generating dust during weighing, keep the container closed when not in use, and consult the manufacturer's safety data sheet before first handling and before disposal.
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