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Description
Epothilone B is a chemical compound widely used in pharmacological and biochemical research. It plays a crucial role in laboratory settings by enabling scientists to study the mechanisms of cancer therapy. This compound is known for its ability to interfere with cellular microtubules, a key component in cell division. As a pharmaceutical research reagent, it supports the development of new therapeutic approaches by providing insights into how drugs interact with cellular structures. Its significance lies in its potential to contribute to advancements in oncology and related fields.
The properties that make Epothilone B a preferred choice include its molecular complexity and stability under specific conditions. These characteristics ensure that the compound remains active during extended experimental periods, making it reliable for both short-term and long-term studies. Additionally, its strong biological activity makes it ideal for use in in vitro and in vivo assays. This combination of stability and potency allows researchers to conduct accurate and reproducible experiments, enhancing the reliability of their findings.
In Indonesian laboratories, Epothilone B is commonly used by researchers in universities and research institutions. It is frequently found in projects focused on drug development and the understanding of cellular responses to antitumor agents. Its application spans various research areas, including cancer biology and the study of cell growth mechanisms. This widespread use underscores its importance as a key reagent in pharmaceutical and biochemical research within the country.
Laboratory Applications
Cancer Research: Epothilone B is used to study the effects of microtubule inhibitors on cancer cell proliferation, aiding in the development of targeted therapies.
Drug Development: It supports the screening of new compounds for their ability to disrupt microtubule formation, which is critical in antitumor drug discovery.
Cell Biology Studies: Researchers use Epothilone B to investigate cellular responses to chemotherapy agents, particularly in the context of apoptosis and cell cycle regulation.
Pharmacological Testing: It is employed in in vitro assays to evaluate the efficacy and mechanism of action of potential therapeutic agents.
Toxicology Research: Epothilone B helps in assessing the cytotoxic effects of compounds on various cell lines, contributing to safety evaluations in drug development.
Specifications
Brand: TCI
CAS number: 152044-54-7
Category: Life Science > Biochemicals and Reagents > Pharmaceutical Research Reagents
Pack sizes: Available in various quantities as per standard laboratory reagent packaging
Physical form: Solid powder (as per standard product specifications)
Storage note: Store in a cool, dry place away from light and moisture
Handling and Storage
Epothilone B should be stored in a cool, dry environment, away from direct light and moisture to maintain its stability and potency. It is recommended to use airtight containers to prevent exposure to air and humidity, which could affect its chemical integrity. In laboratory settings, it is important to handle the compound with appropriate personal protective equipment, such as gloves and safety goggles, to ensure safety during handling. Due to its biological activity, it should be kept in a secure area to prevent accidental exposure. Proper labeling and storage conditions are essential to maintain the quality and effectiveness of the reagent for research purposes.
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