TCI
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Description
TCI E1462 Etoxazole with CAS number 153233-91-1 is a fluorinated oxazoline compound known in the literature as an acaricide, an active mite-control substance that works by disrupting chitin formation during the egg and larval stages. In the laboratory context, this compound is supplied as a research material and reference standard compound, not as a ready-to-use agricultural product. Researchers employ it for residue studies in foodstuffs, toxicology investigations, pest resistance mechanism research, and the development of analytical methods for agricultural samples and their processed products.
The properties that make this compound widely studied are its oxazoline structure bearing a difluorophenyl substituent and an alkoxy ether group, which together confer relatively high chemical stability along with strong lipophilic character. This lipophilicity governs how the compound behaves in fatty food matrices and forms the basis for solvent selection and extraction procedures in residue analysis. Its low solubility in water means that stock solutions are generally prepared using organic solvents such as acetonitrile or acetone. The specific mode of action on chitin synthesis also makes it a useful model compound for mechanistic work.
In Indonesian laboratories, TCI E1462 Etoxazole is typically used within food safety testing programmes, agricultural product quality control, and academic research in agrochemistry and toxicology. It supports the preparation of calibration solutions and comparison standards for chromatographic residue analysis on horticultural commodities and processed products. University research groups and analytical service laboratories also use it when validating extraction and detection methods that must handle lipophilic residues in complex sample matrices.
Laboratory Applications
- Pesticide residue analysis in food commodities, where the compound serves as a comparison standard for identifying and confirming etoxazole residues in horticultural samples and their processed derivatives.
- Toxicology studies, in which the defined chemical identity of this oxazoline compound allows researchers to evaluate biological responses under controlled and reproducible experimental exposure conditions.
- Pest resistance mechanism research, since its specific action on chitin formation during egg and larval stages provides a clear mechanistic target for investigating how resistance develops.
- Analytical method development and validation, where its strong lipophilic character makes it a demanding and therefore informative test analyte for extraction and clean-up procedure optimisation.
- Cell biology and nutrition research applications, where the compound functions as a well-characterised reference material for studies examining chitin synthesis interference and related biochemical pathways.
Specifications
- Brand: TCI (Tokyo Chemical Industry)
- CAS Number: 153233-91-1
- Catalogue Number: E1462
- Category: Life Science > Cell Biology > Nutrition Research
- Pack Sizes: available in standard research-scale packaging; please confirm the currently offered sizes when ordering
- Storage: store according to the conditions stated on the product label and accompanying documentation
Handling and Storage
Store TCI E1462 Etoxazole in a tightly closed original container, kept in a cool, dry and well-ventilated area away from direct sunlight, heat sources and incompatible materials. Because the compound has low water solubility and is handled with organic solvents such as acetonitrile or acetone, prepare and dilute stock solutions inside a fume hood. Use amber glass or chemically compatible vessels for solution storage, label all prepared solutions clearly, and keep containers sealed to limit solvent evaporation. Wear a laboratory coat, safety goggles and suitable chemical-resistant gloves throughout handling. As an acaricidal research compound, avoid inhalation of dust or aerosols, prevent skin and eye contact, and dispose of residues and contaminated consumables through the laboratory's chemical waste stream in accordance with applicable regulations and the supplier's safety data sheet.
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