Ethyl 2-Bromothiophene-3-carboxylate TCI E1573

Name: TCI E1573 632325-50-9 Ethyl 2-Bromothiophene-3-carboxylate
Brand: TCI
SKU: TCI2510E157329627
Price: 4251450.0 IDR
Availability: InStock

Rp 4.251.450,00

Sale Sold out

Shipping calculated at checkout.

Berat 1g

Pembayaran hanya melalui request quotation dan dilakukan setelah tim kami menghubungi Anda. Mohon cantumkan nomor WhatsApp aktif untuk konfirmasi pesanan & pembuatan invoice. Estimasi pengiriman 4-5 minggu setelah pembayaran.

Description

Ethyl 2-Bromothiophene-3-carboxylate is a heterocyclic building block based on a thiophene ring that carries two different functional groups at adjacent positions: a bromine atom at the 2-position and an ethyl ester group at the 3-position. This combination makes it a highly practical starting point for synthetic chemists who build molecular frameworks step by step. In the laboratory, the compound serves as a key intermediate in the preparation of substituted thiophene derivatives, which are frequently encountered in research on active pharmaceutical ingredients, dyes, and organic electronic materials.

The characteristic that makes this material a preferred choice lies in the orthogonality of its two functional groups. The carbon–bromine bond on the thiophene ring is a site responsive to transition-metal-catalysed cross-coupling reactions, while the ester group can be hydrolysed, reduced, amidated, or used as an electronic director without disturbing the bromine position. The thiophene ring itself is electron-rich and aromatic, providing adequate thermal stability during synthetic work. It is precisely this bifunctional nature that allows researchers to design short synthetic routes with fewer protection steps.

In Indonesian laboratories, this building block is typically used in university and institutional research settings where substituted thiophene scaffolds are assembled for medicinal chemistry, materials chemistry, and organic synthesis method development. It is handled on a research scale by chemists working on cross-coupling methodology, heterocycle functionalisation, and the preparation of intermediates that are subsequently elaborated into more complex target molecules through sequential transformations.

Laboratory Applications

Transition-metal-catalysed cross-coupling reactions: the carbon–bromine bond at the 2-position acts as a responsive site for coupling, allowing new carbon–carbon or carbon–heteroatom bonds to be formed selectively.
Synthesis of substituted thiophene derivatives: the compound functions as a key intermediate from which a wide range of ring-substituted thiophene structures can be assembled step by step.
Active pharmaceutical ingredient research: substituted thiophene derivatives prepared from this building block are frequently encountered in medicinal chemistry programmes exploring new bioactive scaffolds.
Dye chemistry: the electron-rich aromatic thiophene core prepared from this intermediate is relevant to research on coloured compounds requiring conjugated heterocyclic frameworks.
Organic electronic materials development: thiophene derivatives derived from this bifunctional intermediate are widely applied in research on organic electronic materials and conjugated systems.

Specifications

Brand: TCI
Catalogue number: E1573
CAS number: 632325-50-9
Category: Chemistry > Building Blocks > Heterocyclic Building Blocks
Pack sizes: available in standard TCI research-scale packaging; please confirm the size required when ordering
Storage: store according to the conditions stated on the manufacturer's label and safety data sheet

Handling and Storage

Store the container tightly closed in a cool, dry, well-ventilated area away from direct sunlight, heat sources, and incompatible materials, following the conditions stated on the manufacturer's label and safety data sheet. Keep the material in its original supplier container or in a chemically compatible sealed vessel that protects it from moisture and air. Handle in a fume hood using appropriate personal protective equipment, including safety glasses, gloves, and a laboratory coat. Avoid contact with skin and eyes and avoid inhaling vapours. Label all secondary containers clearly and dispose of residues and contaminated materials in accordance with institutional chemical waste procedures.