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Description
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanine is a chemical compound widely used in peptide synthesis and biochemical research. This compound is a protected form of L-alanine, featuring the fluoren-9-ylmethoxykarbonyl (Fmoc) group. Its role in the laboratory is critical for constructing complex peptide chains with high precision. The Fmoc protection allows for controlled and sequential amino acid incorporation, making it a fundamental building block in synthetic chemistry.
The compound is favored for its chemical stability, controlled reactivity, and efficiency in peptide reactions. The Fmoc group enables selective deprotection, allowing researchers to manipulate amino acids step by step. This property is essential for creating peptides with specific sequences and functionalities. Additionally, its relatively non-toxic nature ensures safe handling in laboratory environments, contributing to its popularity among researchers.
In Indonesian laboratories, this compound is a key reagent in various scientific studies. It is commonly used in organic chemistry, biochemistry, and pharmacology research. Local scientists rely on it for developing new compounds or studying protein mechanisms. Its versatility and reliability make it a preferred choice for both academic and industrial research settings.
Laboratory Applications
Peptide Synthesis: This compound is ideal for constructing complex peptide sequences due to its Fmoc protection, which allows for controlled and sequential amino acid addition.
Biochemical Research: Its use in biochemical studies enables the investigation of protein structures and interactions, supporting advancements in biotechnology and pharmaceutical research.
Organic Chemistry Experiments: The compound's stability and reactivity make it a valuable tool in organic synthesis, particularly in the development of novel compounds and functional molecules.
Drug Development: It plays a crucial role in the synthesis of drug candidates, aiding in the creation of bioactive peptides for therapeutic applications.
Analytical Protein Studies: The compound supports the analysis of protein structures and functions, contributing to the understanding of biological processes at the molecular level.
Specifications
Brand: TCI
CAS number: 35661-39-3
Category: Chemistry > Chemical Biology > Peptide Chemistry
Pack sizes: Available in various quantities as per supplier specifications
Physical form: Solid powder
Storage note: Store in a cool, dry place away from light and moisture
Handling and Storage
This compound should be stored in a cool, dry environment, away from direct light and moisture to maintain its chemical integrity. It is recommended to use airtight containers to prevent exposure to humidity and contaminants. Due to its controlled reactivity, it should be handled with care, using appropriate personal protective equipment such as gloves and safety goggles. In laboratory settings, it is important to ensure proper ventilation and to follow standard safety protocols to minimize any potential risks. Its relatively non-toxic nature still necessitates cautious handling to maintain a safe working environment.
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