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TCI

CAS 101555-62-8

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-proline TCI F0606

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-proline TCI F0606

Chemical Identity

Other names
N-Fmoc-D-proline · Fmoc-D-Pro-OH
CAS No.
101555-62-8
PubChem
CID 688136·SID 87559659
Formula
C20H19NO4
Molecular weight
337.38 g/mol
Purity
>98.0%(HPLC)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
(2R)-1-(9H-fluoren-9-ylmethoxycarbonyl)pyrrolidine-2-carboxylic acid
SMILES
C1CC(N(C1)C(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)C(=O)O
InChIKey
ZPGDWQNBZYOZTI-GOSISDBHSA-N
MDL
MDL00077067
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N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-proline is a chemical compound widely used in organic and biochemical research, particularly in peptide synthesis. This compound plays a critical role in the formation of peptide chains, especially in methods that involve the use of fluorenyl protecting groups. Its unique structure allows for precise control over chemical reactions, making it an essential tool in modern synthetic chemistry. In laboratory settings, it is frequently employed to facilitate reactions that require both specificity and stability, contributing to the efficiency and accuracy of peptide synthesis processes.

The compound is valued for its chemical stability and controlled reactivity, which are key factors in its popularity among researchers. Its ability to withstand reactive conditions minimizes degradation during synthesis, ensuring consistent results. The molecular structure of N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-proline is complex, offering advantages in the synthesis of peptides by enabling accurate coupling and cleavage reactions. These properties make it a preferred choice for applications requiring high precision and reliability in chemical processes.

In Indonesian laboratories, this compound is commonly used in organic chemistry, biochemical research, and pharmacological studies. It supports a wide range of experimental protocols, particularly those involving the synthesis of peptides and proteins. Its application is widespread across academic and research institutions, contributing to advancements in various scientific fields.

TCI brochures (PDF)

  • Peptide Synthesis: This compound is ideal for peptide synthesis due to its fluorenyl protecting group, which allows for selective coupling and cleavage reactions.
  • Biochemical Research: It supports the study of protein structures and functions by enabling controlled chemical modifications in complex biological systems.
  • Organic Chemistry Experiments: Its stability and reactivity make it a valuable reagent in synthetic pathways requiring precise chemical transformations.
  • Drug Development: It is used in the synthesis of bioactive molecules, aiding in the design of pharmaceutical compounds with specific therapeutic properties.
  • Analytical Chemistry: Its well-defined chemical properties make it suitable for use in analytical methods that require accurate and reproducible results.

Brand TCI
CAS number 101555-62-8
Molecular formula —
Purity —
Category Chemistry > Chemical Biology > Peptide Chemistry
Pack sizes —
Physical form —
Storage Store in a cool, dry place away from light

This compound should be stored in a cool, dry environment, away from direct light and sources of heat. It is recommended to use airtight containers to prevent moisture absorption, which could affect its chemical stability. Due to its reactivity under certain conditions, it should be handled with care, using appropriate personal protective equipment such as gloves and safety goggles. In laboratory settings, it is important to ensure that storage conditions are consistent with standard chemical safety protocols to maintain its integrity and effectiveness. Proper labeling of containers and adherence to safety guidelines are essential to prevent accidental exposure and ensure safe handling.

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