Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-tele-(triphenylmethyl)-D-histidine TCI F1145

Chemical Identity

Other names: Nalpha-Fmoc-tele-trityl-D-histidine · Fmoc-D-His(Trt)-OH
CAS No.: 135610-90-1
Formula: C40H33N3O4
Molecular weight: 619.72 g/mol
Purity: >97.0%(HPLC)
Storage: 0-10°C

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-tritylimidazol-4-yl)propanoic acid
SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)N4C=C(N=C4)CC(C(=O)O)NC(=O)OCC5C6=CC=CC=C6C7=CC=CC=C57
InChIKey: XXMYDXUIZKNHDT-DIPNUNPCSA-N
MDL: MDL00077061
PubChem: CID 44828577

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TCI F1145, with the CAS number 135610-90-1, is a complex chemical compound used in chemical biology, particularly in peptide chemistry. It is a specialized reagent that plays a crucial role in the synthesis of peptides with specific functional properties. The compound features a unique molecular structure, combining an N-alpha-(fluoren-9-ylmethoxykarbonyl) group with a tele-triphenylmethyl moiety attached to D-histidine. This structure makes it a valuable tool for researchers aiming to design and develop peptides with targeted biological activities.

The compound's stability under controlled conditions, along with its ability to participate in controlled chemical reactions, makes it a preferred choice for advanced synthetic processes. Its molecular design allows for precise modifications, enabling the creation of peptides with specific interactions, such as receptor binding or enzymatic activity. These properties are essential for applications in drug development and molecular research. Additionally, its chemical reactivity supports the formation of complex molecular architectures, enhancing its utility in laboratory settings.

In Indonesian laboratories, TCI F1145 is commonly used in biomedical and pharmacological research. Its role in synthesizing peptides with specific biological functions makes it a key component in studies related to drug discovery, diagnostic tools, and molecular interactions. Researchers rely on its unique structure and controlled reactivity to achieve accurate and reproducible results in their experiments. The compound's versatility supports a wide range of applications, making it an essential reagent for advanced chemical synthesis.

Peptide Synthesis: TCI F1145 is ideal for peptide synthesis due to its unique molecular structure, enabling the creation of peptides with specific biological activities.
Drug Development: The compound supports the development of pharmaceutical compounds by facilitating the synthesis of peptides with targeted receptor interactions.
Diagnostic Research: Its ability to form peptides with specific functions makes it suitable for diagnostic applications, including the development of biomarker-based assays.
Molecular Interactions Studies: TCI F1145 is used to study molecular interactions, allowing researchers to investigate binding affinities and functional properties of peptides.
Biomedical Research: The compound plays a vital role in biomedical studies, contributing to the understanding of biological processes and therapeutic applications.

Brand	TCI
CAS number	135610-90-1
Molecular formula	—
Purity	—
Category	Chemistry > Chemical Biology > Peptide Chemistry
Pack sizes	Available in various quantities as per standard laboratory reagent packaging
Physical form	Solid, typically in powder form
Storage	Requires storage in a cool, dry place away from light

TCI F1145 should be stored in a cool, dry environment, away from direct light to maintain its chemical stability. It is recommended to use airtight containers to prevent moisture absorption, as the compound is sensitive to humidity. Proper labeling of storage containers is essential to ensure safe handling. In laboratory settings, it should be handled using appropriate personal protective equipment, such as gloves and safety goggles, to minimize exposure. Due to its chemical reactivity, it should be stored separately from incompatible substances. Regular monitoring of storage conditions is advised to ensure the integrity of the compound during long-term use.

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