TCI
Guanidine Thiocyanate [for Biochemical Research] TCI G0360
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Description
Guanidine Thiocyanate is a chemical compound widely used in biochemical research, particularly in protein denaturation processes. It plays a crucial role in laboratories by disrupting the secondary and tertiary structures of proteins, enabling efficient separation and analysis of biological components. This compound is commonly employed in RNA and DNA extraction procedures, where it helps in breaking down complex protein matrices. Its effectiveness in denaturation makes it an essential reagent for various molecular biology applications.
One of the key properties that make Guanidine Thiocyanate a preferred choice is its ability to lower the melting point of proteins and inhibit enzymatic activity. It is colorless, highly soluble in water, and chemically stable under specific conditions, which ensures consistent performance in laboratory settings. These characteristics allow it to function effectively across a range of reaction conditions, making it a versatile tool for researchers. Its stability and solubility also contribute to its reliability in different experimental protocols.
In Indonesian laboratories, Guanidine Thiocyanate is extensively used in biomedical, biotechnology, and analytical chemistry research. It is a vital component in the processing and analysis of biomolecules, especially in facilities focused on molecular biology and biochemistry. Its role in denaturation and protein separation supports a wide array of scientific investigations, making it a standard reagent in many research environments.
Laboratory Applications
- RNA and DNA extraction where protein denaturation is required to isolate nucleic acids effectively.
- Protein separation from complex mixtures to facilitate purification and analysis in biochemical studies.
- Denaturation of proteins in analytical procedures to study structural changes and functional properties.
- Biochemical research involving the disruption of protein structures for molecular characterization.
- Sample preparation for electrophoresis and other analytical techniques that require protein denaturation.
Specifications
- Brand: TCI
- CAS number: 593-84-0
- Category: Life Science > Biochemicals and Reagents > Denaturation
- Pack sizes: Available in various quantities as per standard laboratory reagent packaging
- Physical form: Colorless liquid or solid, depending on concentration and formulation
- Storage note: Store in a cool, dry place away from direct sunlight and incompatible materials
Handling and Storage
Guanidine Thiocyanate should be stored in a cool, dry location, away from direct sunlight and incompatible substances. It is recommended to use sealed containers to prevent moisture absorption and contamination. Due to its chemical nature, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles, to ensure laboratory safety. Proper ventilation is essential when working with this compound to minimize exposure risks. It is important to follow standard laboratory safety protocols to maintain a safe working environment. Always ensure that storage conditions are suitable for the specific form and concentration of the compound being used.
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