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TCI

CAS 184475-35-2

Gefitinib TCI G0546

Gefitinib TCI G0546
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Description

Gefitinib (TCI G0546, CAS 184475-35-2) is a chemical compound widely used in pharmacological and biochemical research. It functions as an inhibitor of the Epidermal Growth Factor Receptor (EGFR), a critical protein involved in cell growth and proliferation. In laboratory settings, Gefitinib plays a vital role in studying the activation mechanisms of EGFR and its impact on cellular processes. Its application extends to the investigation of cancer-related pathways, making it a valuable tool for researchers aiming to understand and develop targeted therapies.

One of the key attributes that make Gefitinib a preferred choice is its chemical stability and solubility in organic solvents such as ethyl acetate and acetone. These properties ensure consistent performance in various experimental conditions, enhancing the reliability of research outcomes. Additionally, its availability in multiple packaging options allows for flexibility in experimental design and usage. The compound's well-documented properties and reproducibility make it a trusted reagent in both academic and industrial research environments.

In Indonesian laboratories, Gefitinib is commonly used in health, pharmaceutical, and biomedical research. It supports studies related to cancer biology, drug development, and therapeutic interventions. Its role in exploring EGFR inhibition makes it essential for advancing research in oncology and molecular medicine. Due to its accuracy and reliability, Gefitinib is frequently selected by researchers for its consistent performance and scientific relevance.

Laboratory Applications

  • Cancer Research: Gefitinib is used to study EGFR inhibition in tumor cells, helping to identify potential therapeutic targets for lung and other cancers.
  • Drug Development: It serves as a key reagent in the screening of compounds for their ability to inhibit EGFR, aiding in the discovery of new cancer treatments.
  • Toxicology Studies: Gefitinib is employed in toxicity assays to evaluate the effects of EGFR inhibitors on cell viability and metabolic activity.
  • Enzymatic Activity Testing: Its use in enzyme assays allows researchers to assess the impact of EGFR inhibition on cellular signaling pathways.
  • Cell Response Analysis: Gefitinib is used to investigate how cells respond to EGFR inhibition, providing insights into drug efficacy and resistance mechanisms.

Specifications

  • Brand: TCI
  • CAS Number: 184475-35-2
  • Category: Life Science > Biochemicals and Reagents > Pharmaceutical Research Reagents
  • Pack Sizes: Available in various quantities to suit different experimental needs
  • Physical Form: Solid (as per standard product description)
  • Storage Note: Store in a cool, dry place away from direct light

Handling and Storage

Gefitinib should be stored in a cool, dry environment, away from direct sunlight and moisture. It is recommended to keep the compound in a sealed container to prevent contamination and maintain its chemical integrity. Due to its solubility in organic solvents, it is important to handle Gefitinib with appropriate personal protective equipment, such as gloves and safety goggles, to ensure laboratory safety. The compound is generally stable under standard storage conditions, making it suitable for long-term use in research applications. Proper labeling and storage practices help maintain the quality and usability of Gefitinib in laboratory settings.

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