2-Isopropyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is an organoboron compound widely used in organometallic chemistry. This reagent plays a crucial role in synthetic processes, particularly in the development of complex organic and heterocyclic compounds. Its unique molecular structure contributes to its reactivity, making it a valuable tool for chemists working in both academic and industrial research settings. The compound is especially noted for its utility in cross-coupling reactions, where it serves as a key component in the synthesis of aromatic and heterocyclic structures.
The compound’s stability under specific conditions and its ability to act as an efficient boron hydride source make it a preferred choice in modern synthetic chemistry. Its reactivity is further enhanced by its capacity to form complexes with various ligands, including halides, alkoxides, and amines. This versatility allows it to be applied in a wide range of chemical transformations, from coupling reactions to functional group modifications. The compound’s predictable behavior and high reactivity contribute to its reliability in laboratory settings.
In Indonesian laboratories, this compound is commonly used in organic chemistry research, particularly in academic institutions and research centers. It is a key reagent in the development of new chemical compounds, including pharmaceuticals and industrial materials. Its application in the Suzuki-Miyaura reaction highlights its importance in the synthesis of aromatic and heterocyclic compounds, supporting innovation in chemical research across the country.
TCI brochures (PDF)
- Suzuki-Miyaura Cross Coupling Reaction 2025-12-01 · p. 19
Related TCI products
- TCI T4407 1609484-75-4 4,4,5,5-Tetramethyl-2-(spiro[fluorene-9,9'-xanthen]-4-yl)-1,3,2-dioxaborolane
- TCI T4387 1160862-12-3 4,4,5,5-Tetramethyl-2-(spiro[fluorene-9,9'-xanthen]-2-yl)-1,3,2-dioxaborolane
- TCI T4061 870004-04-9 4,4,5,5-Tetramethyl-2-(4-vinylphenyl)-1,3,2-dioxaborolane
- TCI T3875 1080632-76-3 2-([1,1':4',1''-Terphenyl]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
- TCI T3831 269410-26-6 4,4,5,5-Tetramethyl-2-(4-phenoxyphenyl)-1,3,2-dioxaborolane
- TCI T3710 171364-83-3 4,4,5,5-Tetramethyl-2-(4-nitrophenyl)-1,3,2-dioxaborolane
- Cross-coupling reactions, such as the Suzuki-Miyaura reaction, benefit from this compound’s ability to form stable boronic acid derivatives, facilitating the synthesis of aromatic and heterocyclic compounds.
- Organic synthesis of complex molecules relies on its reactivity and compatibility with various ligands, enabling efficient functional group transformations in laboratory settings.
- Heterocyclic compound development utilizes its structural versatility, allowing for the construction of diverse molecular frameworks in pharmaceutical and industrial research.
- Boron hydride source applications leverage its stability and efficiency in generating reactive intermediates for synthetic pathways.
- Research in pharmaceutical chemistry incorporates its role in the synthesis of bioactive compounds, supporting drug discovery and development efforts.
| Brand | TCI |
|---|---|
| CAS number | 76347-13-2 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Organometallic Reagents > Organoboron [Organometallic Reagents] |
| Pack sizes | Available in various quantities as per supplier specifications |
| Physical form | Liquid |
| Storage | Store in a cool, dry place away from moisture and direct sunlight |
This compound should be stored in a cool, dry environment, away from moisture and direct sunlight to maintain its stability and reactivity. It is recommended to use airtight containers made of materials that are chemically inert to prevent any unwanted reactions. Due to its chemical nature, proper ventilation should be ensured in the laboratory workspace to minimize exposure. Handling should be done with appropriate personal protective equipment, such as gloves and safety goggles, to ensure safety. The compound should be kept in a designated chemical storage area to prevent accidental contact with incompatible substances. Regular monitoring of storage conditions is advised to ensure the compound remains in optimal condition for use in laboratory applications.
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