L-Leucine-2-naphthylamide Hydrochloride (2-Naphthylamine free) TCI L0037

Chemical Identity

CAS No.: 893-36-7
PubChem: CID 16219549·SID 87572005
Formula: C16H21ClN2O
Molecular weight: 292.80 g/mol
Purity: >98.0%(HPLC)(T)
Reference databases: ChemSpider·ECHA

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: (2S)-2-amino-4-methyl-N-naphthalen-2-ylpentanamide;hydrochloride
SMILES: CC(C)C[C@@H](C(=O)NC1=CC2=CC=CC=C2C=C1)N.Cl
InChIKey: HTHKKWZMEVJWQF-RSAXXLAASA-N

Rp 2.466.450,00

Sale Sold out

Shipping calculated at checkout.

Berat 1g 5g

Pembayaran hanya melalui request quotation dan dilakukan setelah tim kami menghubungi Anda. Mohon cantumkan nomor WhatsApp aktif untuk konfirmasi pesanan & pembuatan invoice. Estimasi pengiriman 2-4 minggu setelah pembayaran.

Dokumen Keamanan & Mutu

↓ Unduh SDS / MSDS (PDF resmi TCI)

CoA (Certificate of Analysis)

Spesifik per batch produksi — diterbitkan dan dikirim bersama barang sesuai nomor lot yang Anda terima.

Contoh CoA segera tersedia.

💬 Minta CoA via WhatsApp

View full details

L-Leucine-2-naphthylamide Hydrochloride is a chromogenic substrate developed specifically for measuring the activity of aminopeptidase enzymes, particularly leucine aminopeptidase. The molecule consists of an L-leucine residue bound to a 2-naphthylamine group through an amide linkage, and it is supplied as the hydrochloride salt to improve solubility and stability. When the enzyme cleaves the amide bond, the liberated naphthylamine group can be detected spectrophotometrically or through the formation of a coloured compound, allowing the rate of the enzymatic reaction to be followed quantitatively in biochemical studies and laboratory diagnostics.

The property that makes this substrate a preferred choice is its specificity toward aminopeptidases that cleave leucine residues at the amino terminus of a peptide chain, so that the measured result reflects the activity of the target enzyme with a low level of background interference. The "2-Naphthylamine free" designation in the product name indicates that the material has been prepared so that the free amine content is suppressed, which is important both for occupational safety and for measurement accuracy, since free amine can generate a background signal. The hydrochloride salt form supports the preparation of consistent assay solutions.

In Indonesian laboratories, this substrate is typically used in biochemistry and enzymology work where aminopeptidase activity must be quantified reliably. Its role in university research laboratories, clinical diagnostic support work, and enzyme characterisation studies rests on the same principle: a defined leucine-bearing substrate whose cleavage produces a readily measured signal. The hydrochloride form simplifies routine solution preparation, making the material practical for repeated assay runs across a working programme.

Related TCI products

Leucine aminopeptidase activity assays, where the L-leucine residue at the amino terminus provides the specific cleavage point the enzyme recognises, giving a direct quantitative readout of enzyme activity.
General aminopeptidase enzymology studies, since the amide linkage to the 2-naphthylamine group releases a detectable chromogenic product whose formation rate can be followed spectrophotometrically over time.
Enzyme kinetics characterisation work, because the substrate delivers a reproducible signal that allows reaction rates to be measured quantitatively rather than estimated from indirect or endpoint observations alone.
Laboratory diagnostic support procedures, where aminopeptidase activity must be determined with low background interference thanks to the suppressed free 2-naphthylamine content of the preparation.
Biochemical method development and assay validation, as the hydrochloride salt form supports consistent preparation of test solutions across repeated runs and between different analytical sessions.

Brand	TCI
CAS number	893-36-7
Molecular formula	—
Purity	—
Category	Chemistry > Chemical Biology > Peptide Chemistry
Pack sizes	please refer to the packaging options listed for this catalogue item
Physical form	—
Storage	store according to the manufacturer's stated conditions on the product label

Product code: L0037
Form: hydrochloride salt, prepared as 2-naphthylamine free

Store the material in its original tightly closed container under the conditions stated by the manufacturer on the product label, protected from moisture and kept away from incompatible substances. Suitable containers include the supplied amber or opaque chemical bottle, which limits light exposure and helps maintain the integrity of the substrate during storage. Handle the substance in a well-ventilated area or within a fume hood, wearing a laboratory coat, chemical-resistant gloves, and eye protection. Avoid the generation of dust when weighing, close the container promptly after use, and prepare working solutions only in clean labelled glassware. Dispose of residues and contaminated consumables through the laboratory's established chemical waste route.

—