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TCI

CAS 114798-26-4

Losartan TCI L0378

Losartan TCI L0378

Chemical Identity

CAS No.
114798-26-4
PubChem
CID 3961·SID 468592180
Formula
C22H23ClN6O
Molecular weight
422.9 g/mol
Purity
>98.0%(HPLC)(T)
Reference databases
ChEBI·ChemSpider·ECHA·Wikipedia
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
[2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
SMILES
CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)CO)Cl
InChIKey
PSIFNNKUMBGKDQ-UHFFFAOYSA-N
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Losartan is a chemical compound widely used in pharmacological and pharmaceutical research. As a member of the angiotensin-converting enzyme (ACE) inhibitor family, it plays a crucial role in lowering blood pressure by inhibiting the production of angiotensin II, which causes vasoconstriction. This compound is essential for experimental studies in drug development, pharmacological effect analysis, and toxicity testing. Its broad applicability makes it a valuable tool in various laboratory settings, particularly in the fields of pharmaceutical and biomedical research.

Losartan is chemically stable and readily available in solid form, making it a preferred choice for laboratory use. It exhibits good resistance to common laboratory conditions such as moderate temperature and humidity, ensuring consistent performance in experiments. The compound is non-toxic at the concentrations used for research purposes, enhancing its safety profile in laboratory environments. Its availability in various packaging formats also facilitates easy handling and use according to specific experimental needs.

In Indonesian laboratories, losartan is commonly used in pharmaceutical, pharmacological, and health science research. It serves as a raw material, test substance, or control material in various experimental protocols. Its role in drug development and biological activity studies makes it an essential component in both academic and industrial research settings. The compound's reliability and stability further support its widespread use across different research disciplines in Indonesia.

  • Pharmacological research for studying the effects of angiotensin II inhibition in blood pressure regulation.
  • Pharmaceutical development for creating new antihypertensive drugs and related compounds.
  • Toxicity testing to evaluate the safety profile of losartan and its derivatives in experimental models.
  • Biochemical studies involving the synthesis of compounds with specific biological activities.
  • Quality control in the production of pharmaceutical products to ensure consistency and efficacy.

Brand TCI
CAS number 114798-26-4
Molecular formula —
Purity —
Category Life Science > Biochemicals and Reagents > Pharmaceutical Research Reagents
Pack sizes Available in various sizes as per standard laboratory requirements
Physical form Solid
Storage Store in a cool, dry place away from direct sunlight

Losartan should be stored in a cool, dry environment to maintain its chemical stability. It is recommended to keep the compound in airtight containers to prevent moisture absorption and contamination. Laboratory personnel should handle losartan with care, using appropriate personal protective equipment such as gloves and safety goggles. The compound is non-toxic at typical research concentrations, but standard laboratory safety protocols should still be followed. Storage conditions should avoid exposure to extreme temperatures and direct sunlight to ensure long-term stability and usability. Proper labeling of containers is essential for safe handling and accurate identification during experiments.

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