Tos-Ala-OH (Tosylalanine hydroxylamine) is a chemical compound widely used in laboratory settings, particularly in chemical biology and peptide chemistry. This compound plays a crucial role in peptide synthesis and protein modification by serving as a key reagent in activation reactions. Its unique chemical structure, consisting of the amino acid alanine linked to a tosyl sulfonamide group, makes it highly functional in forming peptide bonds. In research environments, Tos-Ala-OH is essential for creating custom peptides and studying molecular interactions.
The reactivity and stability of Tos-Ala-OH make it a preferred choice for various biochemical applications. It exhibits high chemical stability under controlled conditions but becomes highly reactive in low pH or high-temperature environments. This reactivity is advantageous for specialized reactions requiring activation, such as peptide coupling. The compound's ability to participate in controlled chemical transformations makes it a reliable and versatile reagent in synthetic chemistry. Its availability in high purity and dry form further enhances its usability in laboratory experiments.
In Indonesian laboratories, Tos-Ala-OH is extensively used in research related to chemistry, molecular biology, and pharmaceutical sciences. It is commonly applied in academic and industrial research settings to develop new drugs, study protein structures, and conduct biochemical assays. Its role in peptide synthesis and modification has made it a standard component in many research protocols across Indonesia.
- Peptide Synthesis: Tos-Ala-OH is ideal for synthesizing custom peptides due to its ability to form stable peptide bonds during coupling reactions.
- Protein Modification: It is used to modify protein structures by introducing specific functional groups, aiding in the study of protein behavior and interactions.
- Biochemical Assays: The compound's reactivity makes it suitable for biochemical assays where controlled chemical activation is required.
- Molecular Biology Research: Tos-Ala-OH supports research into molecular interactions and structural analysis by enabling precise chemical modifications.
- Drug Development: It is applied in pharmaceutical research to create and test new drug compounds through synthetic peptide pathways.
| Brand | TCI |
|---|---|
| CAS number | 21957-58-4 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Chemical Biology > Peptide Chemistry |
| Pack sizes | Available in various quantities as per standard laboratory supply |
| Physical form | Dry powder |
| Storage | Store in a cool, dry place away from moisture and direct sunlight |
Tos-Ala-OH should be stored in a cool, dry environment to maintain its chemical stability. It is recommended to keep the compound in a tightly sealed container to prevent exposure to moisture and air. Due to its reactivity, it should be handled in a well-ventilated area, and appropriate personal protective equipment should be worn. Avoid contact with incompatible substances, such as strong acids or bases, to ensure safety. The compound is best stored in a desiccator or airtight container to preserve its integrity and effectiveness in laboratory applications.
—
