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TCI

CAS 389-08-2

Nalidixic Acid TCI N0490

Nalidixic Acid TCI N0490

Chemical Identity

CAS No.
389-08-2
PubChem
CID 4421·SID 87573816
Formula
C12H12N2O3
Molecular weight
232.23 g/mol
Purity
>95.0%(T)
Reference databases
ChEBI·ChemSpider·ECHA·Wikipedia
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
SMILES
CCN1C=C(C(=O)C2=C1N=C(C=C2)C)C(=O)O
InChIKey
MHWLWQUZZRMNGJ-UHFFFAOYSA-N
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Nalidixic Acid, with CAS number 389-08-2, is a synthetic antibiotic widely used in biochemical and pharmacological research. It is a key compound in the study of bacterial resistance mechanisms and is particularly effective against Gram-negative bacteria, such as *Escherichia coli* and *Proteus mirabilis*. In laboratory settings, it plays a crucial role in microbiological investigations, enabling scientists to test bacterial susceptibility and develop new therapeutic strategies. Its chemical stability and solubility in organic solvents make it a reliable reagent for various analytical procedures.

Nalidixic Acid is valued for its consistent chemical properties and ease of handling in laboratory environments. Its ability to inhibit bacterial growth makes it an essential tool in microbiological research. The compound’s solubility in organic solvents facilitates its use in chromatographic and spectroscopic analyses. Additionally, its stability under standard laboratory conditions ensures reliable results over time. These properties make it a preferred choice for both academic and industrial research applications.

In Indonesian laboratories, Nalidixic Acid is commonly used in public health, pharmaceutical, and biotechnology research. It is integral to educational programs and government-led research initiatives aimed at improving microbiological analysis capabilities. Its role in antibiotic resistance studies and drug development further highlights its importance in the scientific community.

  • Bacterial Sensitivity Testing: Nalidixic Acid is used to determine the effectiveness of antibiotics against specific bacterial strains, aiding in the development of new treatments.
  • Antibiotic Resistance Research: It helps scientists study how bacteria develop resistance to antibiotics, contributing to the understanding of microbial evolution.
  • Pharmaceutical Development: It serves as a model compound in the formulation and testing of new antimicrobial agents.
  • Microbiological Analysis: Its stability and solubility make it ideal for use in chromatography and other analytical techniques.
  • Educational Research: It is frequently used in academic settings to teach students about antibiotic mechanisms and bacterial behavior.

Brand TCI
CAS number 389-08-2
Molecular formula —
Purity —
Category Life Science > Biochemicals and Reagents > Antibiotics
Pack sizes Available in various quantities as per standard laboratory requirements
Physical form Solid powder
Storage Store in a cool, dry place away from direct sunlight

Nalidixic Acid should be stored in a cool, dry environment to maintain its chemical stability. It is recommended to keep it in a sealed container to prevent moisture absorption and contamination. Due to its potential reactivity, it should be handled with appropriate personal protective equipment, such as gloves and safety goggles. Avoid exposure to heat or direct light to preserve its integrity. In laboratory settings, it should be stored separately from incompatible substances to ensure safety. Regular monitoring of storage conditions is advised to maintain the quality and effectiveness of the compound.

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