n-Octanophenone from TCI is an aromatic ketone. Its structure is a phenyl ring bonded to a carbonyl group, which is in turn joined to a straight alkyl chain. The compound belongs to the alkylphenone homologous series, a family of compounds that share the same core structure while the length of the alkyl chain increases step by step. In the laboratory, n-Octanophenone serves two roles. It is a building block in organic synthesis, and it is a reference compound in chromatography, especially for understanding and validating retention behaviour on reversed-phase columns.
Chemists choose this compound because its two structural features complement each other. The phenyl ketone group absorbs ultraviolet light strongly, so the compound is easy to detect with a UV detector in HPLC. The long alkyl chain gives it fairly high hydrophobicity. Together, these properties make it useful as part of an alkylphenone standard series for assessing column hydrophobicity and selectivity. On the synthesis side, the carbonyl group is a versatile handle. It can be reduced, it can undergo amination, and it can serve as the site for forming new carbon-carbon bonds at the alpha position. That flexibility makes it a practical intermediate for building more complex non-heterocyclic structures.
In Indonesia, n-Octanophenone is used by analytical chemistry laboratories, by quality control laboratories in the pharmaceutical industry, and by organic chemistry research groups at universities. Analytical and quality control teams use it to check reversed-phase HPLC columns and to confirm that chromatographic methods perform consistently. Academic research groups use it as a starting material for synthesis work and in teaching homologous-series concepts. AMI Scientific supplies the TCI grade to support these routine and research workflows.
- Reversed-phase HPLC column evaluation: its long alkyl chain gives high hydrophobicity, so it shows clearly how strongly a stationary phase retains non-polar analytes.
- Alkylphenone homologous standard series: as one member of a regularly increasing chain-length series, it helps analysts map retention against hydrophobicity and compare selectivity between columns.
- UV detector checks in HPLC: the phenyl ketone chromophore absorbs ultraviolet light strongly, giving clear and easily detected peaks for confirming detector response and system suitability.
- Carbonyl reduction and amination studies: the ketone group can be reduced or aminated, so it works well as a model substrate for developing and teaching these organic transformations.
- Alpha-position carbon-carbon bond formation: the carbon next to the carbonyl can serve as a site for new C-C bonds, which makes the compound a useful building block for longer or more functionalised non-heterocyclic molecules.
| Brand | TCI (product code O0149) |
|---|---|
| CAS number | 1674-37-9 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Building Blocks > Non-Heterocyclic Building Blocks |
| Pack sizes | please confirm the available pack sizes with AMI Scientific |
| Physical form | — |
| Storage | follow the conditions on the TCI label and Safety Data Sheet |
- Chemical class: aromatic ketone, part of the alkylphenone homologous series
Keep n-Octanophenone in its original, tightly closed container, clearly labelled, in a cool, dry, well-ventilated place away from direct sunlight, heat sources, and strong oxidising agents. For specific temperature requirements, follow the storage conditions on the TCI label and in the Safety Data Sheet. If you transfer the material, use clean, chemically compatible glass containers with secure caps to prevent contamination and evaporation. Follow standard laboratory precautions when handling it: wear safety glasses, chemical-resistant gloves, and a lab coat, and work in a fume hood or a well-ventilated area. Avoid contact with skin and eyes, and do not breathe any vapour. Review the Safety Data Sheet before use, and dispose of waste according to local regulations and your institution's procedures.
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