Sodium Diatrizoate TCI O0668

Sodium Diatrizoate is the sodium salt of diatrizoic acid, an aromatic compound that carries three iodine atoms on its benzene ring. It is widely known as an iodinated radiographic contrast agent because its iodine atoms absorb X-rays strongly. In the laboratory, its most common role is as a component of density gradient media used to separate blood cells, particularly peripheral blood mononuclear cells. It is also used as a reference material in pharmaceutical and imaging research. This TCI product (catalogue O0668) gives research and teaching laboratories a dependable supply of this well-established compound.

Laboratories choose Sodium Diatrizoate mainly because its aqueous solutions can reach high density. This makes it very useful for preparing separation media that sort particles or cells by differences in density. The compound dissolves readily in water and is usually combined with polysaccharides to give a density and osmolality suitable for living cells. Its high iodine content also makes it useful as a contrast material in experimental X-ray imaging studies and as a standard in the analysis of iodinated compounds. Because it is supplied by TCI, a recognised reagent brand, users get consistent quality across repeated experiments.

In Indonesia, Sodium Diatrizoate is relevant to immunology, haematology and cell biology laboratories at universities and health research institutions that routinely isolate mononuclear cells from blood samples. These laboratories prepare or adjust their own density gradient media for immune cell studies, cell culture work and clinical research projects. Pharmaceutical research groups and imaging research teams may also use it as a reference compound when working with iodinated contrast agents. AMI Scientific supplies it to support this kind of routine research and teaching.

• Density gradient cell separation: its aqueous solutions reach high density, so it is a core component of media used to isolate peripheral blood mononuclear cells from whole blood.
• Preparation of custom separation media: combined with polysaccharides, it lets laboratories adjust density and osmolality so that the resulting medium suits living cells during centrifugation.
• Experimental X-ray imaging studies: its three iodine atoms per molecule absorb X-rays strongly, which makes it a practical contrast material for imaging experiments in research settings.
• Analytical standard for iodinated compounds: its well-defined iodine-rich structure makes it a suitable reference when analysing and comparing other iodinated substances in the laboratory.
• Pharmaceutical and imaging research: as a widely recognised iodinated contrast agent, it serves as a reference material in studies on how contrast agents are formulated and how they behave.

Store Sodium Diatrizoate in its original, tightly sealed container in a cool, dry, well-ventilated area, away from moisture, direct sunlight and incompatible substances. After opening, reseal the container promptly so the material does not absorb moisture. Prepared solutions should go into clean, clearly labelled glass or chemically compatible plastic containers. Follow standard laboratory practice when handling it: wear gloves, safety glasses and a lab coat, avoid creating or breathing in dust, and wash hands after use. Read the Safety Data Sheet supplied with the product before use, and dispose of waste according to local regulations.

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