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CAS 1041434-82-5

Peramivir Trihydrate TCI P2892

Peramivir Trihydrate TCI P2892

Chemical Identity

CAS No.
1041434-82-5
PubChem
CID 154234·SID 468592766
Formula
C15H28N4O4
Molecular weight
328.41 g/mol
Purity
>97.0%(HPLC)(T)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
(1S,2S,3S,4R)-3-[(1S)-1-acetamido-2-ethylbutyl]-4-(diaminomethylideneamino)-2-hydroxycyclopentane-1-carboxylic acid
SMILES
CCC(CC)[C@@H]([C@H]1[C@@H](C[C@@H]([C@H]1O)C(=O)O)N=C(N)N)NC(=O)C
InChIKey
XRQDFNLINLXZLB-CKIKVBCHSA-N
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Peramivir Trihydrate from TCI is the trihydrate form of peramivir, an antiviral compound that inhibits the neuraminidase enzyme of the influenza virus. TCI lists this product under Antibiotics in its catalogue, but pharmacologically peramivir is an antiviral agent, not an antibacterial one. Laboratories use it as a reference compound in virology research, enzyme inhibition assays and pharmaceutical analytical method development. Researchers also often use it as a comparator when evaluating new anti-influenza candidates.

Researchers choose peramivir because its mechanism of action is well characterised. The compound mimics the transition state of the sialic acid substrate and binds strongly to the neuraminidase active site, which stops virus particles from being released from the host cell. This makes peramivir a reliable positive control in both fluorescence-based and chemiluminescence-based neuraminidase activity assays. The trihydrate is a defined solid form, so concentration calculations can be based on the molecular weight of the hydrate. That matters when preparing accurate standard solutions for quantitative work.

In Indonesia, influenza surveillance and infectious disease research remain ongoing priorities for university laboratories, research institutes and public health facilities. Laboratories doing virology studies, neuraminidase inhibition testing or pharmaceutical quality and method development work can use peramivir trihydrate as a well-documented reference material. AMI Scientific supplies this TCI product to support Indonesian research teams that need a consistent, traceable antiviral reference compound for their experimental and analytical programmes.

  • Neuraminidase inhibition assays: peramivir binds strongly to the enzyme's active site, which makes it a dependable positive control for fluorescence and chemiluminescence assay formats.
  • Influenza virology research: its well-characterised mechanism of blocking virus release from host cells makes it a useful benchmark compound in studies of influenza replication.
  • Evaluation of new antiviral candidates: researchers often use peramivir as a comparator to measure the relative inhibitory activity of new anti-influenza compounds under identical assay conditions.
  • Pharmaceutical analytical method development: as a defined trihydrate solid, it can serve as a reference substance when developing and validating methods for the analysis of antiviral compounds.
  • Preparation of standard solutions: because the hydrate form is defined, concentrations can be calculated from the hydrate molecular weight, which supports accurate calibration and quantitative standard preparation.

Brand TCI (product code P2892)
CAS number 1041434-82-5
Molecular formula —
Purity —
Category Life Science > Biochemicals and Reagents > Antibiotics (pharmacologically an antiviral neuraminidase inhibitor)
Pack sizes as listed in the current TCI catalogue; please confirm available sizes with AMI Scientific
Physical form solid (trihydrate form)
Storage follow the conditions on the TCI product label and Safety Data Sheet

Store Peramivir Trihydrate in its original tightly closed container, under the conditions stated on the TCI label and Safety Data Sheet. Protect it from moisture, heat and direct light so that the defined hydrate form, and therefore the accuracy of concentration calculations, is preserved. Keep the container sealed when not in use, and transfer material with clean, dry spatulas. Handle the compound in a well-ventilated area or fume hood, wearing gloves, a laboratory coat and safety glasses. Avoid creating dust and avoid inhalation or skin contact. Label prepared solutions clearly, and dispose of waste according to institutional and local regulations for chemical and bioactive substances.

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