Rifamycin S TCI R0200

Chemical Identity

CAS No.: 13553-79-2
PubChem: CID 12314965·SID 354335535
Formula: C37H45NO12
Molecular weight: 695.8 g/mol
Purity: >98.0%(HPLC)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: [(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21E)-2,15,17-trihydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23,27,29-tetraoxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25-heptaen-13-yl] acetate
SMILES: C[C@H]1/C=C/C=C(/C(=O)NC2=CC(=O)C3=C(C2=O)C(=C(C4=C3C(=O)[C@](O4)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C)O)\C
InChIKey: BTVYFIMKUHNOBZ-URFUDWCHSA-N

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Rifamycin S is a chemical compound widely used in biochemical and pharmacological experiments within laboratory settings. As a member of the rifamycin family of antibiotics, it plays a crucial role in inhibiting bacterial DNA synthesis by targeting the DNA-dependent RNA polymerase enzyme. This mechanism makes it an essential tool for microbiological research, particularly in the isolation and identification of bacteria sensitive to this compound. Its application extends to the study of antibiotic resistance and the development of new therapeutic strategies.

Rifamycin S is preferred due to its high purity and consistent performance, ensuring reliable results in experimental studies. Its chemical stability under specific conditions, combined with its specificity in targeting bacterial enzymes, enhances its utility in precision-based research. However, it is sensitive to light and moisture, requiring careful handling and storage to maintain its integrity. These properties make it a valuable reagent for laboratories requiring accuracy and reproducibility in their experiments.

In Indonesian laboratories, Rifamycin S is commonly used in antibiotic-related research, including studies on bacterial sensitivity and the development of antimicrobial agents. Its stability and effectiveness make it a key component in long-term experiments and in the analysis of microbial responses to various treatments. Its role in both basic and applied research underscores its importance in the scientific community.

TCI brochures (PDF)

Antimicrobials and Antitumor Agents for Research and Experimental Use 2025-04-24 · p. 5
Pharmaceutical Ingredients for Research and Experimental Use 2026-03-09 · p. 5

Related TCI products

Microbial Sensitivity Testing: Rifamycin S is used to determine the susceptibility of bacterial strains to antibiotics, aiding in the identification of effective treatment options.
Antibiotic Resistance Research: It helps in studying how bacteria develop resistance to rifamycin and other antibiotics, contributing to the understanding of drug efficacy.
DNA Polymerase Inhibition Studies: Its ability to inhibit DNA-dependent RNA polymerase makes it a valuable tool in molecular biology experiments focused on gene expression.
Bacterial Isolation and Identification: It is employed in microbiological techniques to isolate and identify bacteria that are sensitive to rifamycin.
Long-term Stability Testing: Its chemical stability under controlled conditions allows for the evaluation of reagent longevity and performance in extended experiments.

Brand	TCI
CAS number	13553-79-2
Molecular formula	—
Purity	—
Category	Life Science > Biochemicals and Reagents > Antibiotics
Pack sizes	Available in various quantities as per standard laboratory reagent packaging
Physical form	Solid
Storage	Store in a cool, dark place away from moisture and direct light

Rifamycin S should be stored in a cool, dark environment to prevent degradation due to light exposure. It is recommended to use airtight containers to protect it from moisture, which can affect its stability. Proper labeling of storage containers is essential to ensure safe handling and prevent contamination. Laboratory personnel should wear appropriate personal protective equipment when handling this compound to minimize exposure. Regular monitoring of storage conditions is necessary to maintain the compound's integrity. Due to its chemical sensitivity, it is important to avoid prolonged exposure to environmental factors that may compromise its effectiveness.

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