Rifabutin TCI R0211

Chemical Identity

CAS No.: 72559-06-9
PubChem: CID 135415564·SID 468592785
Formula: C46H62N4O11
Molecular weight: 847.0 g/mol
Purity: >98.0%(HPLC)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: [(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,32-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1'-(2-methylpropyl)-6,23-dioxospiro[8,33-dioxa-24,27,29-triazapentacyclo[23.6.1.14,7.05,31.026,30]tritriaconta-1(31),2,4,9,19,21,25(32),26,2
SMILES: C[C@H]1/C=C/C=C(\C(=O)NC2=C(C3=C(C4=C(C(=C3O)C)O[C@@](C4=O)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C5=NC6(CCN(CC6)CC(C)C)N=C25)O)/C
InChIKey: AZFBLLCNOQPJGJ-VXTBVIBXSA-N

Rp 2.914.800,00

~~Rp 2.053.800,00~~ Rp 2.914.800,00

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Rifabutin is a chemical compound classified as an antibiotic, specifically a rifamycin derivative. It plays a crucial role in laboratory settings by inhibiting bacterial growth, particularly in cases where bacteria are resistant to other antibiotics. This compound is widely used in microbiological, pharmacological, and biochemical research to study the effectiveness and mechanisms of antibiotics. Its ability to target specific bacterial strains makes it an essential tool for scientists working on antimicrobial resistance and drug development.

Rifabutin is valued for its strong antibacterial properties and its ability to act on the RNA polymerase enzyme, a critical component in bacterial DNA replication. This unique mechanism of action makes it highly effective against both Gram-positive and Gram-negative bacteria, including Mycobacterium tuberculosis. Its chemical stability and potency contribute to its reliability in various experimental conditions, ensuring consistent results in laboratory studies.

In Indonesian laboratories, Rifabutin is commonly used in public health research and the study of infectious diseases. It is a key reagent in the development of new drugs and clinical trials, supporting efforts to combat antibiotic-resistant pathogens. Its application spans multiple disciplines, including microbiology, pharmacology, and biotechnology, making it a versatile and indispensable resource for researchers in Indonesia.

TCI brochures (PDF)

Antimicrobials and Antitumor Agents for Research and Experimental Use 2025-04-24 · p. 5
Pharmaceutical Ingredients for Research and Experimental Use 2026-03-09 · p. 5

Related TCI products

Microbiological research for studying antibiotic resistance in bacterial strains.
Pharmacological studies to evaluate the efficacy and mechanism of action of Rifabutin.
Biochemical experiments aimed at understanding RNA polymerase inhibition in bacterial cells.
Clinical trials for the development of new antimicrobial therapies and treatments.
Public health initiatives focused on combating tuberculosis and other infectious diseases.

Brand	TCI
CAS number	72559-06-9
Molecular formula	—
Purity	—
Category	Life Science > Biochemicals and Reagents > Antibiotics
Pack sizes	Available in standard laboratory quantities
Physical form	Solid powder
Storage	Store in a cool, dry place away from direct sunlight

Rifabutin should be stored in a cool, dry environment to maintain its chemical stability and effectiveness. It is recommended to keep the compound in a tightly sealed container to prevent moisture absorption and contamination. Due to its potent antibacterial properties, it should be handled with appropriate personal protective equipment, including gloves and safety goggles. Laboratory personnel should ensure proper ventilation when working with Rifabutin to minimize exposure. The compound should not be stored near incompatible substances, such as strong oxidizing agents. Regular monitoring of storage conditions is essential to preserve its integrity and ensure safe usage in research settings.

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