TCI T1127 2,3,5,6-Tetrachloroaniline (CAS 3481-20-7) is a halogenated aniline compound carrying four chlorine atoms on its benzene ring. In the laboratory, it is treated as a non-heterocyclic building block for organic synthesis. The amino group can be modified further, while the chlorine substituents provide additional points for structural change. The material suits researchers who need a halogenated aromatic framework with a defined substitution pattern, supplied under the TCI brand for routine synthetic and analytical work.
The four chlorine atoms change the electronic character of both the ring and the amino group compared with ordinary aniline. Because chlorine withdraws electrons, the basicity of the amine is reduced, and this influences its reactivity in reactions such as acylation, diazotization, or condensation. The symmetrical 2,3,5,6 substitution pattern also simplifies the interpretation of spectroscopic data, for example NMR, which is helpful in structural and property studies. For these reasons it is chosen when a heavily halogenated aniline is needed as a starting material or reference compound.
In Indonesian laboratories, this product, offered in a 1 g pack, is well suited to small-scale synthesis research, the development of new compounds, and the preparation of analytical standards or reference materials. The compact pack size lets a laboratory work with a modest quantity, which is practical for exploratory studies and method development. Research groups in universities and industrial R&D facilities can include it in their reagent collections as a dependable halogenated building block for a range of synthetic projects.
- Organic synthesis building block: the reactive amino group and the chlorinated aromatic ring let chemists extend the structure step by step, making this compound a useful starting point for new molecules.
- Acylation and condensation studies: the reduced basicity of the amine, caused by the electron-withdrawing chlorine atoms, makes this aniline a relevant substrate for examining how heavy halogenation affects reaction behavior.
- Diazotization research: researchers exploring diazonium chemistry can use this aniline to observe how a tetrachlorinated ring influences the formation and subsequent transformation of the diazonium intermediate.
- Spectroscopic structure studies: the symmetrical 2,3,5,6 substitution pattern simplifies the interpretation of NMR data, so the compound serves well in investigations linking molecular structure to measured properties.
- Analytical reference material: laboratories that need a highly halogenated aniline as a comparison compound or standard can use this product to support method development and the identification of related substances.
| Brand | TCI |
|---|---|
| CAS number | 3481-20-7 |
| Molecular formula | — |
| Purity | — |
| Category | Chemistry > Building Blocks > Non-Heterocyclic Building Blocks |
| Pack sizes | 1 g |
| Physical form | — |
| Storage | keep tightly closed and consult the supplier's label and safety data sheet for specific conditions |
- Product code: T1127
Store the container tightly closed in a clean, dry, well-ventilated place away from direct heat, sunlight, and incompatible chemicals, following the conditions printed on the supplier's label and safety data sheet. Keep the product in its original container, or transfer it only to a clearly labelled, chemically compatible vessel. As with other halogenated aromatic amines, handle it with care: wear gloves, safety glasses, and a laboratory coat, and work inside a fume hood to avoid inhaling dust or contacting skin. Read the safety data sheet before use, keep a record of its use in the laboratory inventory, and dispose of waste according to local regulations and institutional procedures for halogenated organic waste.
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