Fluorinated Amide Solvents and Fluorinated Sulfonamide Solvents

Fluorinated Amide Solvents and Fluorinated Sulfonamide Solvents — covers specialized solvents based on fluorinated amide and sulfonamide groups, such as trifluoroacetamide and trifluoromethanesulfonamide derivatives, which have high polarity and chemical stability due to the presence of fluorine atoms. The electronic properties of the fluorine groups allow these solvents to dissolve polar compounds while remaining relatively inert toward many organic reactions.

These fluorinated amide and sulfonamide solvents are widely used in organic synthesis as reaction media with low boiling points that are easy to evaporate, especially in fluorination reactions, trifluoroacetylation, and reactions sensitive to moisture. Synthetic chemists also use them as both reagents and solvents in the preparation of organofluorine compounds, including in the protection of amine groups and the modification of active molecules for medicinal chemistry research.

Example products in this collection: TCI T4342 51029-15-3 1-[(Trifluoromethyl)sulfonyl]piperidine, TCI D5063 360-92-9 N,N-Diethyl-2,2,2-trifluoroacetamide, TCI T3262 1547-87-1 2,2,2-Trifluoro-N,N-dimethylacetamide, TCI D6135 28048-17-1 1,1,1-Trifluoro-N,N-dimethylmethanesulfonamide, TCI T2087 340-07-8 1-(Trifluoroacetyl)piperidine, TCI D6323 354-44-9 Dimethylsulfamoyl Fluoride.

When selecting products in this category, consider the water content and purity of the solvent, since residual moisture can interfere with reactions sensitive to water, and pay attention to tightly sealed packaging to maintain stability. All products are genuine products of Tokyo Chemical Industry (TCI) Japan, with purity, packaging, and storage conditions listed on the page of each item.

Other categories at the same level under Solvents, often used together in a single laboratory workflow:

Back to Solvents. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — the official TCI Japan distributor in Indonesia — to check availability and lead time directly from Japan.

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