Collection: Phase Transfer Reaction [Asymmetric Synthesis]

Phase Transfer Reaction [Asymmetric Synthesis] — compiles chiral phase-transfer catalysts, including cinchona alkaloid-derived ammonium salts and binaphthyl-based spiro compounds, which function to transfer reactive species between phases while inducing stereoselectivity. These catalysts enable asymmetric reactions to proceed at the interface of two immiscible phases.

This phase transfer catalyst is used in asymmetric synthesis for enolate alkylation, Darzens epoxidation, and the formation of carbon-carbon and carbon-heteroatom bonds with high stereochemical control. Cinchona-based catalysts such as N-Benzylcinchoninium Chloride are commonly used by organic chemists in the synthesis of unnatural amino acids, while newer spiro binaphthyl catalysts are used for reactions that require higher enantioselectivity.

Examples of products in this collection: TCI B3970 1197922-04-5 (11bS)-2,6-Bis[bis[3,5-bis(trifluoromethyl)phenyl]hydroxymethyl]-3,5-dihydrospiro[4H-dinaphth[2,1-c:1',2'-e]azepine-4,4'-morpholinium] Bromide, TCI D3475 2010983-27-2 6,10-Dibenzyl-N,N'-dimethyl-N,N,N',N'-tetrakis(4-methylbenzyl)-1,4-dioxaspiro[4.5]decane-(2R,3R)-diylbis(methylammonium) Bis(tetrafluoroborate) [=(R,R)-TaDiAS-2nd], TCI B1689 69221-14-3 N-Benzylcinchoninium Chloride [Chiral Phase-Transfer Catalyst], TCI D3476 2135524-59-1 6,10-Dibenzyl-N,N'-dimethyl-N,N,N',N'-tetrakis(4-methylbenzyl)-1,4-dioxaspiro[4.5]decane-(2S,3S)-diylbis(methylammonium) Bis(tetrafluoroborate) [=(S,S)-TaDiAS-2nd], TCI B1684 77481-82-4 N-Benzylquinidinium Chloride [Chiral Phase-Transfer Catalyst], TCI B1683 69257-04-1 N-Benzylcinchonidinium Chloride [Chiral Phase-Transfer Catalyst].

Pay attention to the stereochemical configuration of the catalyst (R,R vs S,S, or cinchonidine vs cinchonine alkaloid), which determines the direction of asymmetric induction, as well as enantiomeric purity so that reaction results remain consistent and reproducible. All products are original Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other parallel categories under Asymmetric Synthesis, often used together in one laboratory workflow:

• Chiral Building Blocks
• Chiral Catalysts, Chiral Ligands, Chiral Reagents
• Chiral Resolution Reagents
• Chiral Resolving Reagents
• Chiral Auxiliaries
• Proline-Based Organocatalysts [Asymmetric Synthesis]

Back to Asymmetric Synthesis. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team, the official distributor of TCI Japan in Indonesia, for availability checks and lead times directly from Japan.