Collection: Proline-Based Organocatalysts [Asymmetric Synthesis]

Proline-Based Organocatalysts [Asymmetric Synthesis] — includes proline derivatives functionalized as chiral organocatalysts, ranging from amides and anilides to silyl-protected prolines. The pyrrolidine ring structure with its chiral center forms the basis of this group's catalytic ability.

These Proline-Based Organocatalysts are used in asymmetric synthesis such as aldol and Michael reactions to selectively build new chiral centers, by synthetic organic chemists in the fields of pharmaceutical chemistry and chiral materials. Their derivatives are also studied as catalysts in other organocatalytic reactions.

Example products in this collection: TCI T3080 1089663-51-3 N-(2-Thiophenesulfonyl)-L-prolinamide, TCI B5701 848821-76-1 (S)-alpha,alpha-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol, TCI B3440 259212-61-8 trans-4-(tert-Butyldiphenylsilyloxy)-L-proline, TCI B5882 948595-00-4 (R)-Bis[3,5-bis(trifluoromethyl)phenyl](pyrrolidin-2-yl)methanol, TCI A0945 64030-44-0 (S)-(+)-2-(Anilinomethyl)pyrrolidine, TCI B6611 848821-61-4 (2S)-2-[Bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]pyrrolidine, TCI T0219 34592-47-7 L-Thioproline, TCI B6927 131180-57-9 (S)-Bis(4-methoxyphenyl)(pyrrolidin-2-yl)methanol.

Pay attention to the stereochemical configuration (L or D), enantiomeric purity, and the type of protecting group or substituent that affects catalytic selectivity. All products are original products of Tokyo Chemical Industry (TCI) Japan, with purity, packaging, and storage conditions listed on each item's page.

Other related categories under Asymmetric Synthesis, often used together in one laboratory workflow:

• Chiral Building Blocks
• Chiral Catalysts, Chiral Ligands, Chiral Reagents
• Chiral Resolution Reagents
• Chiral Resolving Reagents
• Chiral Auxiliaries
• Epoxidation [Asymmetric Synthesis]

Back to Asymmetric Synthesis. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — official distributor of TCI Japan in Indonesia — for availability checks and lead times directly from Japan.