(R)-(-)-2-[Hydroxy(diphenyl)methyl]-1-methylpyrrolidine TCI H0784

Chemical Identity

Other names: (R)-(-)-Diphenyl(1-methylpyrrolidin-2-yl)methanol
CAS No.: 144119-12-0
PubChem: CID 853010·SID 87571148
Formula: C18H21NO
Molecular weight: 267.37 g/mol
Purity: >98.0%(GC)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: [(2R)-1-methylpyrrolidin-2-yl]-diphenylmethanol
SMILES: CN1CCCC1C(C2=CC=CC=C2)(C3=CC=CC=C3)O
InChIKey: XIJAGFLYYNXCAB-QGZVFWFLSA-N
MDL: MDL00145217

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(R)-(-)-2-[Hydroxy(diphenyl)methyl]-1-methylpyrrolidine is a chiral compound widely used in asymmetric synthesis to produce molecules with specific optical configurations. This reagent plays a crucial role in chemical laboratories, particularly in reactions requiring precise stereochiral control. Its chiral nature allows it to act as a catalyst or ligand, enabling the selective formation of desired enantiomers. This makes it an essential tool in the development of pharmaceuticals and complex organic compounds.

The compound's polar nature and solubility in organic solvents such as ethyl acetate and acetone make it highly versatile in synthetic processes. Its stability under various reaction conditions and availability in multiple packaging formats further enhance its appeal. These properties contribute to its reliability and ease of use in both research and industrial settings. Additionally, its ability to influence biological activity through stereochemistry makes it a valuable asset in drug discovery and development.

In Indonesian laboratories, this compound is commonly used by chemists and pharmacologists for the synthesis of new therapeutic agents. Its application is particularly relevant in the development of pharmaceutical compounds, especially in the context of local research initiatives. The compound's role in creating molecules with specific biological activities underscores its importance in both academic and applied research environments.

TCI brochures (PDF)

Proline-type Organocatalysts 2025-01-30 · p. 1
Asymmetric Organocatalysts 2025-06-12 · p. 7
Asymmetric Synthesis 2026-03-18 · p. 6

Related TCI products

Asymmetric synthesis of pharmaceutical compounds due to its chiral structure and ability to control enantiomer formation.
Development of complex organic molecules requiring precise stereochiral control in synthetic pathways.
Catalytic processes in organic reactions where stereochemistry is critical for product specificity.
Ligand-based reactions in transition metal catalysis for enhanced selectivity and efficiency.
Research in drug discovery for the synthesis of compounds with specific biological activities and therapeutic potential.

Brand	TCI
CAS number	144119-12-0
Molecular formula	—
Purity	—
Category	Chemistry > Asymmetric Synthesis > Chiral Catalysts, Chiral Ligands, Chiral Reagents
Pack sizes	Available in various sizes as per supplier specifications
Physical form	Liquid or solid, depending on supplier packaging
Storage	Store in a cool, dry place away from light and moisture

This compound should be stored in a cool, dry environment, away from direct light and moisture to maintain its stability and effectiveness. It is recommended to use airtight containers made of glass or high-density polyethylene to prevent contamination and evaporation. Due to its polar nature, it may require careful handling when working with organic solvents. Always ensure proper ventilation in the laboratory and wear appropriate personal protective equipment such as gloves and safety goggles. Avoid exposure to heat sources and keep the compound away from incompatible materials to ensure safe storage and use.

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