Collection: TNF-α Inhibitors
TNF-α Inhibitors — encompasses compounds that modulate or inhibit tumor necrosis factor-alpha (TNF-α), a key proinflammatory cytokine, including immunomodulatory agents derived from thalidomide and matrix metalloproteinase inhibitors that affect its release from immune system cells.
TNF-α inhibitor compounds such as thalidomide and pomalidomide are used by immunology researchers in studies of immunomodulatory and anti-angiogenic mechanisms in both in vitro and in vivo models. Ilomastat, as a matrix metalloproteinase inhibitor, is used to explore the processing pathway of TNF-α from its membrane-bound form to its soluble form, supporting basic research in inflammation and the immune system.
Example products in this collection: TCI T2524 50-35-1 (+/-)-Thalidomide, TCI I1202 142880-36-2 Ilomastat, TCI P2074 19171-19-8 Pomalidomide.
Pay attention to high analytical purity and a clear stereochemical profile for thalidomide-derived compounds, since small structural differences can affect the results of immunomodulation experiments in laboratory cell cultures. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.
Other parallel categories under Immune System, Inflammation, Allergy Research are often used together within a single laboratory workflow:
Back to Immune System, Inflammation, Allergy Research. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — official distributor of TCI Japan in Indonesia — for availability checks and lead times directly from Japan.
