Collection: NLRP3 Inflammasome Inhibitors

NLRP3 Inflammasome Inhibitors — contains natural and synthetic compounds reported to inhibit activation of the NLRP3 inflammasome complex, including flavonoids, diterpenoids, stilbenoids, and synthetic small molecules studied for their role in innate immune signaling pathways and cellular inflammation research.

Compounds in this category are used by immunology and molecular biology researchers to study the mechanisms of inflammasome activation, IL-1beta cytokine release, and pyroptosis pathways in innate immune cell models such as macrophages. Natural compounds such as resveratrol and isoliquiritigenin are also used as comparators in screening candidate inflammasome modulators and in structure-activity relationship studies.

Example products in this collection: TCI I0822 961-29-5 Isoliquiritigenin, TCI C3469 78574-94-4 Cycloastragenol, TCI V0176 273404-37-8 VX-765, TCI D5062 145108-58-3 Dexmedetomidine Hydrochloride, TCI A3449 84692-91-1 Arglabin, TCI D5955 54863-37-5 Dapansutrile, TCI R0071 501-36-0 Resveratrol, TCI F1187 28808-62-0 Fraxinellone.

When selecting items in this category, consider the compound source (natural vs. synthetic), purity level, salt form for synthetic compounds such as MCC950, and solubility in the assay solvent. All products are genuine Tokyo Chemical Industry (TCI) Japan products, with purity, packaging, and storage conditions listed on each item's page.

Other categories at the same level under Immune System, Inflammation, Allergy Research are often used together in one laboratory workflow:

• Anti-inflammatory Ingredients (for Research and Experimental Use)
• Anti-allergic Ingredients (for Research and Experimental Use)
• GABA Receptor Inhibitors
• NF-κB Activation Inhibitors
• Chemical Mediators
• Metabolic Antagonists

Back to Immune System, Inflammation, Allergy Research. For large-volume procurement, special packaging, or specific grades, contact the AMI Scientific team — official distributor of TCI Japan in Indonesia — for stock availability and lead time directly from Japan.