GW-405833 is a chemical compound used in laboratory settings for its role in neuroscientific and cell biology research. As an active compound, it is specifically designed to inhibit GABA-A receptor activity, a key neurotransmitter receptor in the central nervous system. This compound plays a critical role in studying cellular signaling pathways and how cells respond to external stimuli. Its application spans various research areas, including the investigation of neural function and regulation, making it a valuable tool for scientists working in neuroscience and cell biology.
GW-405833 is preferred due to its chemical stability under specific conditions and its high affinity for its target receptor. These properties ensure reliable and consistent results in experimental settings, which is essential for accurate scientific research. Its ability to be used across multiple analytical methods, such as biological activity assays, toxicity testing, and pharmacological effect evaluations, further enhances its utility. This versatility makes it a go-to choice for researchers seeking precision and reproducibility in their experiments.
In Indonesian laboratories, GW-405833 is commonly used in academic and industrial research institutions focused on neurobiology and cellular signaling. It supports studies related to neurological disorders and drug development. Its application is widespread in both basic and applied research, contributing to advancements in understanding neural mechanisms and developing therapeutic interventions.
- Neurotransmitter receptor inhibition studies benefit from GW-405833's ability to selectively block GABA-A receptors, aiding in understanding synaptic transmission and neural signaling pathways.
- Cellular signaling pathway research utilizes this compound to investigate how external stimuli influence intracellular responses and signal transduction mechanisms.
- Pharmacological effect testing employs GW-405833 to evaluate the efficacy and mechanism of action of potential therapeutic agents targeting GABAergic systems.
- Toxicity assessment protocols incorporate this compound to study its impact on neuronal cells and assess its safety profile under various experimental conditions.
- Drug development programs use GW-405833 as a tool to screen and validate compounds for their potential in treating neurological and psychiatric disorders.
| Brand | TCI |
|---|---|
| CAS number | 180002-83-9 |
| Molecular formula | — |
| Purity | — |
| Category | Life Science > Cell Biology > Cell Signaling and Neuroscience |
| Pack sizes | — |
| Physical form | — |
| Storage | Store in a cool, dry place away from light and moisture |
GW-405833 should be stored in a cool, dry environment to maintain its chemical stability and prevent degradation. It is recommended to keep the compound in a tightly sealed container to minimize exposure to moisture and air. Laboratory personnel should handle the material with care, using appropriate personal protective equipment such as gloves and safety goggles. Proper ventilation should be ensured when working with the compound to avoid inhalation of vapors. Due to its specific target affinity, it is important to follow standard laboratory safety protocols to ensure safe handling and prevent any unintended interactions. Always store the compound in a designated chemical storage area that is inaccessible to unauthorized individuals.
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