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TCI

CAS 121-66-4

2-Amino-5-nitrothiazole TCI A0381

2-Amino-5-nitrothiazole TCI A0381

Chemical Identity

CAS No.
121-66-4
PubChem
CID 8486·SID 87562024
Formula
C3H3N3O2S
Molecular weight
145.14 g/mol
Purity
>98.0%(HPLC)(T)
Reference databases
ChEBI·ChemSpider·ECHA
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
5-nitro-1,3-thiazol-2-amine
SMILES
C1=C(SC(=N1)N)[N+](=O)[O-]
InChIKey
MIHADVKEHAFNPG-UHFFFAOYSA-N
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2-Amino-5-nitrothiazole is a chemical compound widely used as a building block in the synthesis of complex heterocyclic compounds. It plays a crucial role in organic chemistry laboratories, where it serves as a versatile intermediate for the development of pharmaceuticals, pesticides, and industrial chemicals. Its unique molecular structure, featuring a thiazole ring with amino and nitro groups, makes it an essential component in various synthetic pathways. This compound is particularly valued for its ability to participate in multiple reaction types, including substitution and ring-opening reactions, which are fundamental to the creation of bioactive molecules.

The stability of its chemical structure and controlled reactivity make 2-Amino-5-nitrothiazole a preferred choice for researchers. It exhibits compatibility with a range of reagents, including acids, bases, and organic solvents, allowing for flexible synthetic strategies. Its inert nature under normal conditions ensures safe handling in laboratory environments, reducing the risk of unintended side reactions. These properties contribute to its reliability and effectiveness in both academic and industrial research settings.

In Indonesian laboratories, 2-Amino-5-nitrothiazole is extensively used in organic chemistry research, particularly in pharmacology and the synthesis of active compounds. It is a common reagent in university laboratories and research institutions, supporting studies aimed at developing new drugs and agrochemicals. Its availability and chemical versatility make it a staple in the chemical supply chain for Indonesian scientists working in diverse fields of chemistry.

  • Pharmaceutical research utilizes 2-Amino-5-nitrothiazole for synthesizing bioactive compounds due to its structural versatility and reactivity in organic synthesis.
  • Pesticide development benefits from this compound as it can be modified to create compounds with specific biological activities against pests and pathogens.
  • Industrial chemical synthesis relies on this compound for the production of various intermediates used in manufacturing processes.
  • Organic chemistry education incorporates this compound as a key building block for teaching synthetic methods and reaction mechanisms.
  • Drug discovery programs use 2-Amino-5-nitrothiazole to explore new molecular scaffolds with potential therapeutic applications.

Brand TCI
CAS number 121-66-4
Molecular formula —
Purity —
Category Chemistry > Building Blocks > Heterocyclic Building Blocks
Pack sizes Available in various quantities as per standard laboratory supply
Physical form Solid
Storage Store in a cool, dry place away from direct sunlight and moisture

2-Amino-5-nitrothiazole should be stored in a cool, dry environment to maintain its chemical stability. It is recommended to keep the compound in airtight containers to prevent exposure to moisture and air, which could affect its reactivity. Suitable storage containers include glass or polyethylene bottles with secure lids. In laboratory settings, it is important to handle the compound with appropriate personal protective equipment, such as gloves and safety goggles, to ensure safe handling. Due to its controlled reactivity, it is generally safe to use under standard laboratory conditions, provided proper safety protocols are followed. Regular monitoring of storage conditions ensures the compound remains in optimal condition for use in research applications.

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