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CAS 186020-66-6

tert-Butyl 12-Hydroxy-4,7,10-trioxadodecanoate TCI B5587

tert-Butyl 12-Hydroxy-4,7,10-trioxadodecanoate TCI B5587

Chemical Identity

Other names
12-Hydroxy-4,7,10-trioxadodecanoic Acid tert-Butyl Ester · tert-Butyl 3-[2-(2-(2-Hydroxyethoxy)ethoxy)ethoxy]propionate · 3-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]propionic Acid tert-Butyl Ester
CAS No.
186020-66-6
PubChem
CID 3625858·SID 354335165
Formula
C13H26O6
Molecular weight
278.35 g/mol
Purity
>97.0%(GC)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
tert-butyl 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]propanoate
SMILES
CC(C)(C)OC(=O)CCOCCOCCOCCO
InChIKey
KSXVEOLRERRELV-UHFFFAOYSA-N
MDL
MDL03791106
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*tert*-Butyl 12-Hydroxy-4,7,10-trioxadodecanoate is a heterobifunctional PEG linker featuring a terminal hydroxyl group and a protected *tert*-butyl ester, enabling controlled stepwise conjugation. It is widely utilized in the synthesis of PEGylated biomolecules, including drug-protein conjugates, surface-modified nanoparticles, and targeted delivery systems. The trioxa spacer enhances aqueous solubility and reduces immunogenicity, making it an essential building block in chemical biology and pharmaceutical research applications.

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