2-Bromobenzaldehyde Dimethyl Acetal TCI B5827

Chemical Identity

Other names: 1-Bromo-2-(dimethoxymethyl)benzene
CAS No.: 35849-09-3
PubChem: CID 11148943·SID 468590728
Formula: C9H11BrO2
Molecular weight: 231.09 g/mol
Purity: >98.0%(GC)

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: 1-bromo-2-(dimethoxymethyl)benzene
SMILES: COC(C1=CC=CC=C1Br)OC
InChIKey: RXYLXDKWPRPXMI-UHFFFAOYSA-N
MDL: MDL07780683

Rp 1.326.150,00

~~Rp 927.150,00~~ Rp 1.326.150,00

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2-Bromobenzaldehyde Dimethyl Acetal is a protected benzaldehyde building block in which the aldehyde functionality is masked as a dimethyl acetal, enabling selective transformations at the aromatic ring under basic or nucleophilic conditions. The ortho-bromo substituent facilitates efficient cross-coupling reactions, including Suzuki, Heck, and Sonogashira couplings, making it a versatile intermediate in complex molecule construction. Following coupling, mild acidic hydrolysis deprotects the acetal to regenerate the aldehyde group, allowing further derivatization in the synthesis of pharmaceuticals, agrochemicals, and advanced materials.