TCI B6376, (ethoxymethyl)benzene (CAS 539-30-0), also known as benzyl ethyl ether, is a simple aromatic ether that serves as a valuable model substrate in synthetic methodology research. Its benzylic C–H bonds are comparatively weak and readily abstracted, making the compound a common benchmark in C–H functionalisation, selective oxidation, and photoredox catalysis studies. The benzyl–oxygen bond can also be cleaved by hydrogenolysis, so the compound frequently appears in discussions of benzyl protecting-group strategy. AMI Scientific supplies this TCI building block in 1 g and 5 g pack sizes for research and advanced teaching laboratories.
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