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Description
TCI B6380, methyl 5-bromo-2-hydroxybenzoate (CAS 4068-76-2), also known as methyl 5-bromosalicylate, is a trifunctional building block bearing a phenolic hydroxyl, a methyl ester, and an aryl bromide on a single compact scaffold. The phenol can be alkylated or acylated, the ester hydrolysed or converted to amides, and the bromide engaged in palladium-catalysed cross-coupling, allowing chemists to sequence transformations exactly as their route requires. The adjacent hydroxyl and carbonyl groups also make it a convenient precursor to salicylate-type chelating ligands and Schiff bases for coordination chemistry. AMI Scientific supplies this TCI building block in 5 g and 25 g pack sizes for medicinal chemistry, ligand design, and materials research.
