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TCI

CAS 2212-06-8

2-[(4-Bromophenoxy)methyl]oxirane TCI B6472

2-[(4-Bromophenoxy)methyl]oxirane TCI B6472

Chemical Identity

Other names
1-(4-Bromophenoxy)-2,3-epoxypropane · 4-Bromophenyl Glycidyl Ether · 4-Bromophenyl 2,3-Epoxypropyl Ether
CAS No.
2212-06-8
PubChem
CID 102766
Formula
C9H9BrO2
Molecular weight
229.07 g/mol
Purity
>97.0%(GC)
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
2-[(4-bromophenoxy)methyl]oxirane
SMILES
C1C(O1)COC2=CC=C(C=C2)Br
InChIKey
YKUYKENINQNULY-UHFFFAOYSA-N
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2-[(4-Bromophenoxy)methyl]oxirane, also known as 4-bromophenyl glycidyl ether, pairs a strained epoxide with a brominated aromatic ring. Nucleophilic ring opening of the oxirane provides rapid access to beta-amino alcohols and related functionalised scaffolds. The aryl bromide remains available for subsequent palladium-catalysed cross-coupling, enabling orthogonal synthetic strategies. TCI supplies this building block in 5 g and 25 g sizes for research laboratory use.

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  • Kan et al. (2011). Crystal structure of 2,4-bis((4-bromophenoxy)methyl)- 1,3,5-trimethylbenzene, C23H22Br2O2. Zeitschrift für Kristallographie - New Crystal Structures doi:10.1524/ncrs.2011.0180

References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.