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Description
Bretylium tosylate (CAS 61-75-6) is a quaternary ammonium compound long recognised in the literature as an adrenergic neuron blocker that interferes with norepinephrine release from sympathetic nerve terminals. It is widely used as a reference pharmacological tool in cardiovascular and autonomic nervous system research, including studies of antiarrhythmic mechanisms and cardiac repolarisation. The material is supplied strictly for research and experimental use and is not intended for human diagnostic or therapeutic application. AMI Scientific offers a 25 mg pack size suitable for isolated tissue experiments and cell-based assays.
Scientific References
- Fallen (2000). Bretylium Tosylate (UDATE—2000). Cardiac Electrophysiology Review doi:10.1023/a:1026583112967
- Muhammad et al. (1999). The effect of bretylium tosylate on ECG-guided pericardiocentesis. Annals of Emergency Medicine doi:10.1016/s0196-0644(99)80198-x
- DeBehnke (1991). Effects of bretylium tosylate during experimental cardiac arrest. The American Journal of Emergency Medicine doi:10.1016/0735-6757(91)90064-q
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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