Bisdemethoxycurcumin TCI B6548

Chemical Identity

Other names: Bisdesmethoxycurcumin · Curcumin III · (1E,6E)-1,7-Bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione
CAS No.: 33171-05-0
PubChem: CID 5315472
Formula: C19H16O4
Molecular weight: 308.33 g/mol
Purity: >95.0%(HPLC)(T)
Storage: 0-10°C
Reference databases: ChEBI·ChemSpider·Wikipedia

Full identifiers (IUPAC, SMILES, InChIKey)

IUPAC: (1E,6E)-1,7-bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione
SMILES: C1=CC(=CC=C1C=CC(=O)CC(=O)C=CC2=CC=C(C=C2)O)O
InChIKey: PREBVFJICNPEKM-YDWXAUTNSA-N
MDL: MDL03419284

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Bisdemethoxycurcumin (CAS 33171-05-0) is one of the three principal curcuminoids found in turmeric rhizome, differing from curcumin by the absence of methoxy groups on both aromatic rings. It is commonly used as a reference compound for curcuminoid profiling by HPLC or TLC, and for in vitro bioactivity studies where a single, defined curcuminoid is preferred over a crude extract. Curcuminoids are light sensitive and degrade under alkaline conditions, so the material should be stored cool, dry, and protected from light, with working solutions prepared fresh. AMI Scientific supplies it in a 1 g pack size for research and experimental use.

TCI brochures (PDF)

Phytochemicals 2025-12-17 · p. 12
Pharmaceutical Ingredients for Research and Experimental Use 2026-03-09 · p. 24

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Mohammadi et al. (2018). Inhibition of amyloid fibrillation of lysozyme by bisdemethoxycurcumin and diacetylbisdemethoxycurcumin. Biophysical Chemistry doi:10.1016/j.bpc.2018.02.005
Lappichetpaiboon (2025). Anticandidal effects of bisdemethoxycurcumin & melatonin with dual light emitting diode in photodynamic therapy. Photodiagnosis and Photodynamic Therapy doi:10.1016/j.pdpdt.2025.104797
Jayaprakasha et al. (2006). Antioxidant activities of curcumin, demethoxycurcumin and bisdemethoxycurcumin. Food Chemistry doi:10.1016/j.foodchem.2005.06.037

References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.