Bisdemethoxycurcumin (CAS 33171-05-0) is one of the three principal curcuminoids found in turmeric rhizome, differing from curcumin by the absence of methoxy groups on both aromatic rings. It is commonly used as a reference compound for curcuminoid profiling by HPLC or TLC, and for in vitro bioactivity studies where a single, defined curcuminoid is preferred over a crude extract. Curcuminoids are light sensitive and degrade under alkaline conditions, so the material should be stored cool, dry, and protected from light, with working solutions prepared fresh. AMI Scientific supplies it in a 1 g pack size for research and experimental use.
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- Mohammadi et al. (2018). Inhibition of amyloid fibrillation of lysozyme by bisdemethoxycurcumin and diacetylbisdemethoxycurcumin. Biophysical Chemistry doi:10.1016/j.bpc.2018.02.005
- Lappichetpaiboon (2025). Anticandidal effects of bisdemethoxycurcumin & melatonin with dual light emitting diode in photodynamic therapy. Photodiagnosis and Photodynamic Therapy doi:10.1016/j.pdpdt.2025.104797
- Jayaprakasha et al. (2006). Antioxidant activities of curcumin, demethoxycurcumin and bisdemethoxycurcumin. Food Chemistry doi:10.1016/j.foodchem.2005.06.037
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