4-[(tert-Butoxycarbonyl)amino]bicyclo[2.1.1]hexane-1-carboxylic Acid TCI B6609

Name: TCI B6609 1050886-56-0 4-[(tert-Butoxycarbonyl)amino]bicyclo[2.1.1]hexane-1-carboxylic Acid
Brand: TCI
SKU: TCI2510B660913565
Price: 5577600.0 IDR
Availability: InStock

Rp 5.577.600,00

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Berat 100mg

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Description

TCI B6609 is 4-[(tert-butoxycarbonyl)amino]bicyclo[2.1.1]hexane-1-carboxylic acid, a compact and rigid saturated building block. It carries orthogonal carboxylic acid and Boc-protected amine handles on opposite bridgehead positions, allowing stepwise elaboration. The bicyclo[2.1.1]hexane core is actively studied as a three-dimensional bioisostere for ortho- and meta-substituted benzene rings in drug discovery. AMI Scientific supplies this TCI building block in a 100 mg pack size for medicinal chemistry and advanced synthesis laboratories.

Scientific References

Wang et al. (2013). A scalable synthesis of (1R,3S,5R)-2-(tert-butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid. Tetrahedron Letters doi:10.1016/j.tetlet.2013.09.114
Bakonyi et al. (2013). Synthesis of All Four Stereoisomers of 3-(tert-Butoxycarbonyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic Acid. The Journal of Organic Chemistry doi:10.1021/jo4013282
Kadyrov et al. (2021). Convenient Synthesis of (R)-3-[(tert-Butoxycarbonyl)amino]piperidine and (R)-3-[(tert-Butoxycarbonyl)amino]azepane. Synthesis doi:10.1055/a-1526-7657

References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.