TCI B6627 Benzenesulfonyl Fluoride (CAS 368-43-4) is a core SuFEx click chemistry reagent supplied by TCI and available at AMI Scientific. The S–F bond offers greater hydrolytic stability than the corresponding sulfonyl chloride while remaining selectively activatable, enabling clean sulfonamide and sulfonate ester formation. It is widely used in chemical biology as a covalent labelling reagent and in studies of serine-residue enzyme modification. Offered in 1 g and 5 g packs, it must be stored tightly closed in a cool, dry place away from moisture, amines, and strong bases.
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- (2007). 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride (AEBSF). Cold Spring Harbor Protocols doi:10.1101/pdb.caut2453
- (2007). AEBSF (4-[2-Aminoethyl]benzenesulfonyl fluoride hydrochloride). Cold Spring Harbor Protocols doi:10.1101/pdb.caut856
- Wagner (2023). Preparation of 4-(5-(p-Tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonyl fluoride (ArSO2F). Organic Syntheses doi:10.15227/orgsyn.100.0382
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
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