TCI B6627 Benzenesulfonyl Fluoride (CAS 368-43-4) is a core SuFEx click chemistry reagent supplied by TCI and available at AMI Scientific. The S–F bond offers greater hydrolytic stability than the corresponding sulfonyl chloride while remaining selectively activatable, enabling clean sulfonamide and sulfonate ester formation. It is widely used in chemical biology as a covalent labelling reagent and in studies of serine-residue enzyme modification. Offered in 1 g and 5 g packs, it must be stored tightly closed in a cool, dry place away from moisture, amines, and strong bases.
Related TCI products
- TCI T4302 944453-80-9 2,4,6-Tris(trifluoromethyl)benzenesulfonyl Chloride
- TCI T3508 220227-84-9 3-(Trifluoromethoxy)benzenesulfonyl Chloride
- TCI T2146 94108-56-2 4-(Trifluoromethoxy)benzenesulfonyl Chloride
- TCI T1910 777-44-6 3-(Trifluoromethyl)benzenesulfonyl Chloride
- TCI T1892 776-04-5 2-(Trifluoromethyl)benzenesulfonyl Chloride
- TCI T1795 2991-42-6 4-(Trifluoromethyl)benzenesulfonyl Chloride
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- (2007). 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride (AEBSF). Cold Spring Harbor Protocols doi:10.1101/pdb.caut2453
- (2007). AEBSF (4-[2-Aminoethyl]benzenesulfonyl fluoride hydrochloride). Cold Spring Harbor Protocols doi:10.1101/pdb.caut856
- Wagner (2023). Preparation of 4-(5-(p-Tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonyl fluoride (ArSO2F). Organic Syntheses doi:10.15227/orgsyn.100.0382
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