TCI C0139, 3-Chlorobenzoyl Chloride (CAS 618-46-2), is a highly reactive aromatic acid chloride bearing a meta chlorine substituent. It is used as an acylating agent for the preparation of esters, amides, and aryl ketones, including Friedel-Crafts acylation. The reagent is corrosive and moisture sensitive, so anhydrous conditions and fume-hood handling are essential. AMI Scientific supplies it in 25 g packs in original manufacturer packaging for equipped research laboratories.
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- Johansen et al. (2012). Molecular conformational structures of 2-fluorobenzoyl chloride, 2-chlorobenzoyl chloride, and 2-bromobenzoyl chloride by gas electron diffraction and normal coordinate analysis aided by quantum chemical calculations. Structural Chemistry doi:10.1007/s11224-012-0169-x
- Raja et al. (2014). Structural Investigation on Pharmaceutical Intermediate o-Chlorobenzoyl Chloride: A DFT Approach. Asian Journal of Chemistry doi:10.14233/ajchem.2014.15461
- Ou et al. (1996). Inverse phase transfer catalysis. Kinetics of the pyridine 1-oxide-catalyzed reaction of chlorobenzoyl chloride and chlorobenzoate ion. Journal of Molecular Catalysis A: Chemical doi:10.1016/1381-1169(96)00059-3
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