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Description
TCI C0424 Crotonoyl Chloride (CAS 10487-71-5) is supplied as a mixture of cis- and trans- isomers and serves as a versatile non-heterocyclic building block. Its highly reactive acyl chloride group allows rapid formation of crotonate amides and esters under mild conditions. The conjugated double bond provides a second handle for Michael additions, cycloadditions, and polymer chemistry. The compound is moisture sensitive and corrosive, so it must be handled in a fume hood with dry glassware and appropriate protective equipment.
Scientific References
Zakeri et al. (2013). ChemInform Abstract: A New One‐Pot Synthesis of 1,2,4‐Oxadiazoles from Aryl Nitriles, Hydroxylamine and Crotonoyl Chloride.. ChemInformdoi:10.1002/chin.201352138
References were compiled automatically from Crossref and every DOI was verified to exist. AMI Scientific is not affiliated with the authors or the publishers.
