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TCI

CAS 618-48-4

3-Chlorobenzamide TCI C0562

3-Chlorobenzamide TCI C0562
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TCI C0562 3-Chlorobenzamide (CAS 618-48-4) is a meta-chlorinated aromatic amide supplied as a non-heterocyclic building block for research use. The amide group can be hydrolysed to the corresponding carboxylic acid, dehydrated to the nitrile, or reduced to the benzylamine, giving synthetic chemists several routes from a single starting material. It is also valued as a directing group in transition metal catalysed C–H functionalisation and as a hydrogen-bonding motif in crystal engineering studies. Store the crystalline solid in a tightly closed container in a cool, dry, light-protected place and handle it with gloves and eye protection.

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  • Qingxiang et al. (2000). Study on the Hydrolysis of 2-Chlorobenzamide. Journal of Agricultural and Food Chemistry doi:10.1021/jf990163a
  • (2024). Docking studies, molecular structure, and spectroscopic analysis of 3-chlorobenzamide as an anti-cancer agent. Indian Journal of Biochemistry and Biophysics doi:10.56042/ijbb.v61i4.8236
  • Zhao et al. (2013). Crystal structure of 14-O-[(4-chlorobenzamide-2-methylpropane-2-yl)-thioacetate] mutilin diethanol solvate, C37H58ClNO7S. Zeitschrift für Kristallographie - New Crystal Structures doi:10.1524/ncrs.2013.0154

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