TCI C0975 3-Chlorocinnamic Acid (CAS 1866-38-2) is the meta-substituted isomer of chlorocinnamic acid, supplied as a crystalline solid in a 25 g pack. Its carboxylic acid and conjugated alkene provide convenient sites for esterification, amidation, reduction, and conjugate addition. The meta chlorine placement makes it a useful counterpart to the ortho and para isomers in structure–activity studies. Handle the powder with gloves and eye protection in a well-ventilated area and store it tightly closed in a cool, dry place.
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- KANAO et al. (1991). ChemInform Abstract: Topochemical Studies. Part 13. Structures of 3‐Bromocinnamic Acid and 3‐Chlorocinnamic Acid.. ChemInform doi:10.1002/chin.199114052
- Kim et al. (2012). Dependence of the solid-state photomechanical response of 4-chlorocinnamic acid on crystal shape and size. CrystEngComm doi:10.1039/c2ce25811k
- Sun et al. (2000). A novel ortho-dehalogenation reaction of 2-chlorocinnamic acid catalyzed by the pink yeast Rhodotorula rubra Y-1529. Chemosphere doi:10.1016/s0045-6535(99)00316-1
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