TCI C1102 1-(2-Chlorophenyl)piperazine (CAS 39512-50-0) is an arylpiperazine heterocyclic building block for organic and medicinal chemistry. Its free secondary nitrogen readily undergoes alkylation, acylation and sulfonylation, giving fast access to diverse derivative series. The ortho-chloro aromatic ring adds a distinctive steric and electronic profile useful in structure–activity work. AMI Scientific offers this TCI product in 5 g and 25 g packs; please refer to the official TCI documentation for specifications and safe handling.
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- MENDELSON et al. (1990). Sex differences in the effects of 1-(m-trifluoromethylphenyl) piperazine and 1-(m-chlorophenyl) piperazine on copulatory behavior in the rat. Neuropharmacology doi:10.1016/0028-3908(90)90133-c
- (2015). Spectroscopic Investigation (FT-IR, FT-Raman, NMR and UV-Vis),Conformational Stability, NBO and Thermodynamic Analysis of 1-(2-Methoxyphenyl) Piperazine and 1-(2-Chlorophenyl) Piperazine by DFT Approach. Pharmaceutica Analytica Acta doi:10.4172/2153-2435.1000391
- El-Naby (2019). Potentiometric Signal Transduction for Selective Determination of 1-(3-Chlorophenyl)piperazine “Legal Ecstasy” Through Biomimetic Interaction Mechanism. Chemosensors doi:10.3390/chemosensors7030046
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