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Description
TCI C1318 4(5)-Cyanomethylimidazole combines a tautomeric imidazole ring with a reactive acetonitrile side chain. The nitrile group can be reduced to a primary amine, hydrolysed to an acid or amide, or converted into a tetrazole bioisostere. Because the side chain sits one carbon from the ring, it gives rapid access to histamine- and histidine-related scaffolds valued in medicinal chemistry. AMI Scientific supplies this TCI heterocyclic building block in 1 g and 5 g packs for laboratory research.
