TCI C1463 cis-1,2-Cyclohexanediamine is an alicyclic diamine bearing two adjacent primary amine groups in the cis configuration. It serves as a versatile bidentate ligand for transition metal complexes and as a precursor to Schiff bases, ureas, amides, and macrocyclic frameworks. The rigid cyclohexane backbone provides well-defined conformational control that is valuable in coordination chemistry and catalysis research. AMI Scientific offers this reagent in original TCI packaging, and users should handle it under dry conditions because primary amines readily react with atmospheric moisture and carbon dioxide.
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- Lee et al. (2018). Practical synthesis of four different pseudoenantiomeric organocatalysts with both cis- and trans-substituted 1,2-cis-cyclohexanediamine structures from a common intermediate. Tetrahedron doi:10.1016/j.tet.2018.05.035
- Lee et al. (2017). Practical Synthesis of Two Different Pseudoenantiomeric Organocatalysts with cis‐Cyclohexanediamine Structure from a Common Chiral Source. Asian Journal of Organic Chemistry doi:10.1002/ajoc.201700229
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