TCI C1538, 3-Chloro-2,2-dimethyl-1-propanol (CAS 13401-56-4), is a bifunctional neopentyl-type building block bearing both a primary alcohol and a chloride group. This dual functionality allows selective transformations, including nucleophilic substitution at the chloride site, esterification or etherification at the hydroxyl group, and intramolecular cyclization. The quaternary carbon centre provides steric bulk that is frequently exploited to improve the stability of derived products. Available from AMI Scientific in 25 g and 500 g packs, it should be kept tightly closed in a cool, dry place away from moisture.
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