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Description
TCI C1542, (S)-(+)-3-Chloro-1,2-propanediol (CAS 60827-45-4), is a versatile chiral three-carbon synthon carrying two hydroxyl groups and one chloride. Base treatment converts it into an enantiomerically defined glycidol derivative, opening routes to chiral amino alcohols, modified glycerol frameworks, and chiral ligands. Its defined S configuration allows stereochemistry to be controlled from the very first step of a synthetic sequence. Available from AMI Scientific in 10 g and 25 g packs, it should be handled in a fume hood and stored tightly closed in a cool, dry place.
