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TCI

CAS 456-04-2

2-Chloro-4'-fluoroacetophenone TCI C1977

2-Chloro-4'-fluoroacetophenone TCI C1977

Chemical Identity

CAS No.
456-04-2
PubChem
CID 120248·SID 87561686
Formula
C8H6ClFO
Molecular weight
172.58 g/mol
Purity
>98.0%(GC)
Reference databases
ChemSpider·ECHA
Full identifiers (IUPAC, SMILES, InChIKey)
IUPAC
2-chloro-1-(4-fluorophenyl)ethanone
SMILES
C1=CC(=CC=C1C(=O)CCl)F
InChIKey
UJZWJOQRSMOFMA-UHFFFAOYSA-N
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2-Chloro-4'-fluoroacetophenone is a versatile organic compound widely used in laboratory settings for its reactivity and structural versatility. As a fluorinated building block, it plays a crucial role in the synthesis of aromatic and heterocyclic compounds, which are fundamental in pharmaceutical and industrial chemistry. Its unique combination of chlorine and fluorine atoms contributes to its chemical stability and reactivity, making it an essential reagent in various synthetic pathways. This compound is commonly employed in research to develop new chemical structures with specific functional groups and properties.

The compound's reactivity stems from its electron-withdrawing groups, which influence its behavior in substitution and electrophilic reactions. The presence of both chlorine and fluorine atoms enhances its polarity and reactivity, allowing it to participate in a wide range of chemical transformations. These properties make it a preferred choice for chemists seeking to create complex molecular architectures with precise functionalization. Its ability to undergo various reaction mechanisms also makes it adaptable to different synthetic strategies in organic chemistry.

In Indonesian laboratories, 2-Chloro-4'-fluoroacetophenone is frequently used in organic chemistry research, particularly in pharmaceutical development and industrial chemical synthesis. Its role as a key building block in the creation of specialized compounds makes it a valuable resource for researchers working on drug discovery, material science, and chemical innovation. Its availability and chemical properties make it a go-to reagent for laboratories requiring high reactivity and structural specificity.

  • Organic synthesis in pharmaceutical research due to its reactivity and structural versatility for creating complex molecules.
  • Industrial chemical production where fluorinated compounds are needed for specialized applications in materials and coatings.
  • Heterocyclic compound development as a key intermediate in the synthesis of nitrogen-containing ring structures.
  • Drug discovery projects requiring precise functional group modification and molecular design.
  • Material science research for the development of advanced polymers and functional materials with tailored properties.

Brand TCI
CAS number 456-04-2
Molecular formula —
Purity —
Category Chemistry > Building Blocks > Fluorinated Building Blocks
Pack sizes Available in various quantities as per supplier specifications
Physical form Solid or liquid, depending on the specific product variant
Storage Store in a cool, dry place away from light and incompatible substances

This compound should be stored in a cool, dry environment, away from direct sunlight and sources of heat. It is recommended to use airtight containers made of materials that are chemically inert, such as glass or high-density polyethylene, to prevent contamination and degradation. Due to its reactivity, it should be handled with care, using appropriate personal protective equipment like gloves and safety goggles. It is important to ensure proper ventilation in the laboratory when working with this compound to minimize exposure. Always store it separately from strong bases and reducing agents to avoid unwanted chemical interactions.

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